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Medical Conditions - Best Disease

The best disease is known as the best vitelliform macular dystrophy. It is a rare autosomal dominant disease that occurs due to mutation of BEST1 (Bestrophin-1), causing incomplete penetration and variable expression presenting in childhood. It commonly affects the macula, a part of the retina present at the back of the eyes. It makes the central vision blurry and causes a blank patch on the center of the vision. There is no treatment for this condition.

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Best Disease - Stages, Diagnosis, Treatment, and Complications

Best vitelliform macular dystrophy, also called Best disease, occurs because of mutations in the BEST-1 gene. Read the article to know more.

4 min readOctober 10, 2022