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Medical Conditions - Hepatosplenomegaly

Hepatosplenomegaly (HPM) is a condition in which both the liver and spleen swell beyond their regular size. It occurs due to a number of reasons such as acute hepatitis, obesity, alcohol consumption, liver cancer, malaria, etc. The symptoms include pain, swelling, fatigue, tenderness, fever, and jaundice.

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Niemann-Pick Disease Radiology: CT, MRI, and Imaging Findings Explained

Radiological findings of Niemann-Pick disease vary by subtype. Imaging shows hepatosplenomegaly, pulmonary infiltrates, and neurological changes in the brain.

6 min readJune 23, 2026