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Neuroplasticity in Rehabilitation: Adapting the Brain for Recovery

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4 min read


The potential of the nervous system to adapt and reorganize in response to new information or stimuli is referred to as neuroplasticity.

Written by

Dr. Sameeha M S

Medically reviewed by

Dr. Abhishek Juneja

Published At May 14, 2024
Reviewed AtMay 15, 2024


The brain is an essential organ for human survival. For a long time, it was believed that the brain was fully developed and generally unchanging after the first few years of life, even though scientists now know that neurons can make new connections during this time. They discovered that nerve fibers continue to grow and innervate cerebral cortex sections in children from the age of three until puberty; even investigations in adults have shown that the brain generates new neurons in a crucial region for learning and memory. This can all be explained by brain plasticity or neuroplasticity, which is equally fascinating as it is complex. Neuroplasticity and rehabilitation are concepts that are strongly associated with the fields of neuroscience and healthcare.

What Is Neuroplasticity?

The term neuroplasticity describes the nervous system's capacity to change the way it is organized or responds to new information or stimuli. This dynamic reconfiguration can help with rehabilitation from stroke, traumatic brain injury, and even neurological conditions (multiple sclerosis and Parkinson's disease). The ability of the brain to alter and expand as a result of experience is referred to as neuroplasticity. There are two types of neuroplasticity:

  • Functional Plasticity - The ability to shift functions from a damaged portion of the brain to uninjured sections is referred to as functional plasticity. Functional plasticity alterations occur as a result of neuron malfunction or damage and are a sort of reactive neuroplasticity.

  • Structural Plasticity - The capacity to alter one's physical structure as a result of understanding something new is known as structural plasticity. As individuals learn and mature, the central nervous system produces and integrates new neurons. Changes in gray matter percentage or synaptic strength constitute examples of structural plasticity. A consistent meditation practice, for example, can result in an increased amount of gray matter in the brain.

What Are the Applications of Neuroplasticity?

Neuroplasticity is used in the field of rehabilitative medicine in a variety of ways. The brain may grow, change, and evolve well into old age, proving that the brain is not programmed with permanence.

  • Rehabilitation for Brain Damage - Functional plasticity allows for the transfer of brain activity related to a certain function from a damaged part of the brain to an unharmed part of the brain. The functional results of physical therapy following a stroke are explained, at least in part, by neuroplasticity, whereby patients improve function with an afflicted limb through treatments like electrical stimulation or constraint-induced movement therapy.

  • Meditation - Studies on meditation have connected meditative activities to variations in gray matter thickness or density. By altering the physical makeup of the brain, neuroplasticity may be used to treat conditions including anxiety, melancholy, fear, and aggression.

  • Management of Pain - People who endure chronic pain may feel discomfort in areas that may have previously been harmed but are now healthy. It is possible that the nervous system's maladaptive remodeling is what's causing this chronic discomfort. With improvements in the understanding of neuroplasticity, medical professionals may be able to rewire how the brain processes pain signals and how the nervous system reacts to signals. Examples include using meditation to help with fibromyalgia management or mirror therapy to ease discomfort from phantom limbs.

  • Blindness and Deafness - Hearing-impaired people have improved eyesight or other senses because their auditory cortex is employed for purposes other than hearing. The same holds true for those who are blind, whose additional senses may be more developed. For instance, some blind people have learned to use human echolocation to detect and navigate their environment. According to studies, those who use click-echo navigation process the sounds in the visual rather than the auditory hemispheres of the brain.

  • Multilingualism - The ability of the brain to change can be increased by learning many languages. While additional research is needed, studies have revealed that bilinguals have better organizing and analytical skills as well as longer attention spans.

How Can Neuroplasticity Help the Brain Adapt and Change During the Rehabilitation Process?

The brain's capacity to adapt and change during the rehabilitation process depends significantly on neuroplasticity. In reaction to trauma, illness, or learning, it enables the brain to rearrange its neuronal networks. When a portion of the brain is injured, other healthy areas can develop new abilities or fortify connections to replace the missing ones. This rewiring may aid in recovery during therapy.

Neuroplasticity helps the brain heal after suffering damage from incidents like stroke or traumatic injury. The ability to alter particular synapses and neural pathways has significant ramifications for clinical physiotherapeutic therapies that will enhance health. The present understanding of brain plasticity, which is currently the focus of considerable study for several pathologies underpins promising therapeutics including targeted exercise training, cognitive training, and neuropharmacology. The patient's quality of life will be enhanced by a better knowledge of the mechanisms driving neuroplasticity following brain injury or nerve damage.

What Are the Neurological Conditions or Injuries That Are Treated by Neuroplasticity-Focused Rehabilitation?

Rehabilitation that focuses on neuroplasticity can help people who have a variety of neurological disorders and traumas. But it works especially well in instances where the brain's capacity to adjust and restructure its neural networks is crucial to recovery. The following neurological conditions and injuries stand to gain the most from rehabilitation that emphasizes neuroplasticity:

  • Stroke - This condition disrupts the blood flow to the brain, causing damage to the brain. Rehabilitation that emphasizes neuroplasticity and includes physical, occupational, and speech therapy can aid stroke victims in regaining lost abilities like movement, speech, and cognitive capacities.

  • Traumatic Brain Injury - Head trauma can result in traumatic brain injury (TBI), which damages brain tissue. Utilizing neuroplasticity in rehabilitation seeks to assist patients in regaining their cognitive, motor, and sensory abilities.

  • Spinal Cord Injury - Spinal cord trauma can result in paralysis or the loss of feeling. Rehabilitation tries to optimize neuroplasticity in the spinal cord and brain to recover movement and sensation below the damage level. This includes physical therapy and functional electrical stimulation.

  • Neurorehabilitation After Brain Surgery - Brain surgery patients who have had tumors removed or epilepsy surgery may suffer changes in their brain function. The brain can adjust to these changes with the aid of rehabilitation, which will also improve its ability to think and move.


The brain's capacity to adapt and change during the recovery process depends heavily on neuroplasticity. Utilizing activities and experiences that support brain remodeling and recovery, rehabilitation programs make use of this capacity. Healthcare providers can optimize the results of rehabilitation and raise the quality of life for people suffering from neurological injuries or diseases by understanding and using neuroplasticity.

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Dr. Abhishek Juneja
Dr. Abhishek Juneja



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