Hi, Welcome to icliniq.com. Your wife has symptoms of inflammatory arthritis. Ankle arthritis is seen in different conditions like rheumatoid arthritis, spondyloarthropathy, sarcoidosis, and Poncet's disease. Please mention whether she has other symptoms such as pain in the small joints of the hands, backache, hip pain, fever, weight loss, and cough. A thorough history helps us to have a definitive diagnosis.
Hello, Welcome to icliniq.com. You have not mentioned the symptoms of your wife. The treatment of lupus depends on the symptoms and severity of the disease. Some SLE medicines cannot be given during pregnancy. Medicines like Hydroxychloroquine, steroids, and Azathioprine are relatively safe and given according to the severity of symptoms.
Hello, Welcome to icliniq.com. The symptoms you are describing are suggesting a connective tissue disease, most likely primary Sjogren's syndrome. It is an autoimmune disease that presents with dryness of the eyes, mouth, dental caries, fatigue, mild to severe joint pains, body aches, and sometimes neuropathy. However, the possibility of other connective tissue diseases cannot be ruled out without further tests. Do you have any other symptoms like photosensitivity, oral ulcers, rashes anywhere, Raynaud's, any muscle weakness, tingling, or numbness of limbs? Some tests that you need to get done are ENA profile (qualitative), C3, C4, ESR (erythrocyte sedimentation rate), CRP (C-reactive protein), CBC (complete blood count), LFT (liver function test), KFT (kidney function test), urine analysis.
Hello,Welcome to icliniq.com.Your symptoms are multisystemic and challenging to fit into one diagnosis. In the absence of specific symptoms and signs seen in rheumatological diseases, diagnosis is a little uncertain. However, an ESR (erythrocyte sedimentation rate) of 119 is very high and certainly a cause for concern. Neuropathy, vague body aches, brain-related symptoms, and very high ESR can be seen in medium- to large-vessel vasculitis.
Hi, Welcome to icliniq.com. You have not mentioned her arthritis in detail. I assume she has rheumatoid arthritis looking at her pictures (attachments removed to protect the patient's identity). What are her symptoms at present? How much pain and stiffness does she have? The treatment will depend on the severity of arthritis at present. Also, I will need test reports of CBC (complete blood count), ESR (erythrocyte sedimentation rate), and CRP (c-reactive protein).
Hello, Welcome to icliniq.com. Elevated vitamin B12 levels can be seen in certain blood-related conditions like myeloproliferative disorders. It may also be seen in some liver conditions. Since all the remaining values are normal, these conditions seem unlikely in your case. However, to be sure, you can repeat the tests in another six to eight weeks.
Hello, Welcome to icliniq.com. The symptoms you have described could be seen in lupus or other connective tissue diseases. Your ANA (antineutrophil antibody) is repeatedly positive. However, the ANA profile does not show any specific antibody. But that does not confirm that you cannot have a connective tissue disease (attachments removed to protect the patient’s identity).
Hi, Welcome to icliniq.com. You can have these symptoms due to fibromyalgia or hypothyroidism. You have photosensitivity with Raynaud's phenomenon and arthritis. These symptoms can also be seen in lupus or mixed connective tissue disease. As you had a neurological episode, you can have them due to stroke or a transient stroke.
Hello, Welcome to icliniq.com. You have not described the joint pains in detail. So it is difficult to ascertain the cause for joint pains. Which are the joints involved? Any associated swelling or redness of joints? Any early morning stiffness? Whether the pain increases on activity or rest? These are some of the questions that are important in making a diagnosis. Some amount of joint and muscle pains can be seen following COVID infection, which usually subsides in two to three months with or without some anti-inflammatory medicines.
Hello, Welcome to icliniq.com. The symptoms suggest active disease at present. You are currently on a low dose of tablet Sulfasalazine (anti-inflammatory) which can be increased if needed. To control the inflammation, I suggest taking tablet Etoricoxib (non-steroidal anti-inflammatory drug) 120 mg every night for two weeks and to get the following tests done - CBC (complete blood count), ESR (erythrocyte sedimentation rate), CRP (C-reactive protein), AST (aspartate aminotransferase), ALT (alanine aminotransferase) and creatinine. A further change in medication can be suggested after the test reports.
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