Does Tezspire take time to show results?

Question

Hello doctor,

I have been getting Tezspire, a monoclonal antibody used for severe asthma (Tezepelumab) injections every four weeks, but I am still experiencing asthma attacks between doses. It has been about a month since I started, but I have not seen much improvement. Is this normal? Do some people require more frequent dosing? My inhaler use has not decreased much. Should I consider switching to another asthma medication?

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I understand that you are frustrated with the results of Tezspire (Tezepelumab), especially if you are still experiencing asthma attacks and frequent inhaler use. Typically, Tezspire can take a few months to show its full effect, as it works by targeting eosinophils, which play a role in asthma-related inflammation. Most people start seeing significant improvements after two to three months of treatment, but responses can vary.

Some patients may still need additional support from their inhalers, particularly during the early stages of treatment. While more frequent dosing is not common, your doctor may adjust your treatment plan if necessary. I recommend discussing your ongoing symptoms with your doctor—they may want to reassess your overall asthma management or explore other treatment options. Keeping track of your symptoms and how you're feeling will help guide the next steps in your treatment plan.

I hope this helps you.

Thank you.