Common "Best Disease" queries answered by top doctors | iCliniq

Best Disease

The best disease is known as the best vitelliform macular dystrophy. It is a rare autosomal dominant disease that occurs due to mutation of BEST1 (Bestrophin-1), causing incomplete penetration and variable expression presenting in childhood. It commonly affects the macula, a part of the retina present at the back of the eyes. It makes the central vision blurry and causes a blank patch on the center of the vision. There is no treatment for this condition.

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Why surgery will not help my macular hole?

Query: Hello doctor,I have Best's disease and am currently undergoing injections in my left eye, and it is improving. I have now been told that my right eye has a full-blown macular hole, but surgery may not help. Why not?  Read Full »


Dr. Rahul Vaswani

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concern. There are two surgical outcomes of macular hole surgery. First is anatomical correction, that is, whether the gap (hole) that has formed will be filled again or not. Usually, it has a 90 % chance in a macular hole surger...  Read Full »

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