Common "Biopsy" queries answered by top doctors | iCliniq


Biopsy is a diagnostic test which is ordered for the confirmation of diagnosis in certain conditions. In this procedure, a sample of the problematic tissue is removed from the body and sent to a laboratory to be observed under a microscope. There are different types of biopsies based on the procedure used to remove the tissue as well as extent of removal.

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Is biopsy mandatory to operate on an ill-defined thickening in the gall bladder?

Query: Hi doctor, My mother recently underwent endoscopic retrograde cholangiopancreatography (ERCP). She has enhanced ill-defined soft tissue thickening in the gall bladder (neck or cystic duct region), extending to the common hepatic duct and causing abrupt narrowing. Due to this, constructive jaundice o...  Read Full »

Dr. C. Elanchezhian

Answer: Hello, Welcome to I read your query and can understand your concern. In laboratory reports (attachments removed to protect patient's identity), liver enzymes and bilirubin levels are increased. Endoscopic retorgrade cholengipancreatogram (ERCP) report suggests ill-defined soft tissue...  Read Full »

Is radiation therapy required for stage 2B invasive breast carcinoma?

Query: Hi doctor, My mum, who is 75- years- old, recently had a modified radical mastectomy for stage 2B invasive carcinoma (tumor size 3x3, two nodes of 19 dissected had metastasis). Her biopsy result says that NHS-grade 3 and positive lymph vascular and perineural invasion, the skin and areola and nipple...  Read Full »

Dr. Andrew Chellakumar Fenn

Answer: Hi, Welcome to A summary of the patient's diagnosis, cancer stage T2, n1 (tumor 2, node 1), Grade 3, Er pr positive (estrogen and progesterone receptor testing), Lvi pni (lymphovascular and perineural invasion) positive. She is 75 years old with cardiac Comorbidity. I would suggest ra...  Read Full »

Do I have leukemia?

Query: Hi doctor, My blood test shows lymphocytes 60% where the normal range is 20% to 45%. I had immunophenotyping and the values are CD23 - 2.11%, CD19 - 0.30% and CD5 - 79.9%. What does it indicate? Am I a leukemia patient? Please advise.  Read Full »

Dr. Sadaf Mustafa

Answer: Hello, Welcome to I would also like to know the total leukocyte count, platelets, and RBC (red blood cell) count. Have you had an ESR (erythrocyte sedimentation rate) done? Is this the only CBC (complete blood count) you have ever had? Are there any accompanying symptoms like fever, ch...  Read Full »

The back of my right breast hurts while breathing. Please help.

Query: Hello doctor, The back of my right breast hurts, and when I breathe in, it hurts in that area. I cannot even move because it hurts even when I move my right side. This is not related, but every night, I feel as though I have something in my throat, and I have to swallow and cough. I have type 1 di...  Read Full »

Dr. Chandwadkar Ashish

Answer: Hello, Welcome to I can understand your concern. Regarding your first complaint about pain in the back of the right breast even on breathing in and moving, it seems you are suffering from an inflammation of rib cartilage but it cannot be confirmed unless and until ruled out by thoroug...  Read Full »

My testicular USG shows many solid nodules. Is biopsy needed?

Query: Hi doctor, I have had an ultrasound on my testicles and found multiple solid nodules or lumps and lesions in both testicles. He strongly suspects germ cell tumors. I have had blood tests done, and tumor markers and everything else is normal. I will be seeing a urologist in about two weeks. Do I have...  Read Full »

Dr. Arvind Guru

Answer: Hi,Welcome to testicular mass is treated as cancer unless proven otherwise. That is why it is advised to evaluate the lesions found by patient or ultrasound by surgical removal and detailed pathological examination. Whereas for most other sites, the biopsy is possible. The biopsy is ...  Read Full »

What does my biopsy report suggest?

Query: Hello doctor, I have attached my biopsy report. Can you confirm if I am suffering from Crohn's disease? If not, can the report be wrong? Thank you.  Read Full »

Dr. Utkarsh Sharma

Answer: Hi, Welcome back to I understand your concern and will help you regarding it. I have seen the attached report (the attachment was removed to protect the patient’s identity). The histopathological features described are highly indicative of inflammatory bowel disease (IBD) or could b...  Read Full »

I have acute leukemia. Can bone marrow transplant help?

Query: Hello doctor, My friend's brother has been diagnosed with blood cancer and underwent his first chemotherapy three weeks ago. According to the acute leukemia immunophenotyping by flow cytometry report, morphologic and immunophenotypic findings are consistent with acute myeloid leukemia. Immunophenoty...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to Sorry to hear about his ill health. Let me tell you that after seven days of the first round of chemotherapy, a bone marrow biopsy should be done to check for the percentage of the blast. Ideally, it should be less than a five percent blast after the first round of chem...  Read Full »

Do the raised white lines in my mouth indicate leukoplakia

Query: Hi doctor, I went to the ENT for a sore throat. He ended up saying I have leukoplakia. It is mainly in the gap where I am missing the tooth. He said it was in other areas around my lower gum but it pretty much wiped off of there. I then went to my dentist who said it was not leukoplakia. I then went...  Read Full »

Dr. Naveen Thomas

Answer: Hello, Welcome to I have seen the image (attachment removed to protect patient identity). It is not at all a type of leukoplakia as seen in the picture. But, if you are a smoker, then I would recommend you stop smoking. It seems to be just hyperkeratinization of the oral mucosa which ca...  Read Full »

I want to know whether the general functions of mitochondria are checked?

Query: Hello doctor, My brother has done a muscular biopsy. I want to know whether the general functions of the mitochondria have been checked and verified in this muscular biopsy. In the hospital, they have checked the muscular biopsy and they are as follows: ATPases (9.4, 4.63, 4.35), menadione, succinat...  Read Full »

Dr. Ambekar Sudheer

Answer: Hello, Welcome to The diagnosis of mitochondrial disease was based on the presence of characteristic ragged red fibers (RRF) in more than 2 % of muscle fibers in the muscle biopsy (attachment removed to protect patient identity). RRFs are not pathognomonic of mitochondrial diseases,...  Read Full »

What would be the differential diagnosis based on the biopsy report of the cheek?

Query: Hello doctor, If the biopsy report of the cheek (buccal mucosa, left) showed chronically inflamed stratified squamous epithelium and underlying fibrous connective tissue, which contains a number of irregularly shaped vascular spaces approximately the size of normal capillaries that contain numerous ...  Read Full »

Dr. Singh Smrita

Answer: Hello, Welcome to The current biopsy results indicate a lichenoid type of lesion in the buccal mucosa. This type of picture can be seen due to various causes ranging from allergens to systemic drugs, anything causing irritation (like dentures), etc. Though the presence of rash, uveitis,...  Read Full »

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