Biopsy is a diagnostic test which is ordered for the confirmation of diagnosis in certain conditions. In this procedure, a sample of the problematic tissue is removed from the body and sent to a laboratory to be observed under a microscope. There are different types of biopsies based on the procedure used to remove the tissue as well as extent of removal.
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My wife's biopsy report suggests she has grade 2 breast cancer. What does her biopsy report suggest about distant metastasis?
Query: Hi doctor, This is for my wife's breast cancer report. I want your opinion on the case and pathology report. As you can see in the biopsy report, it is the grade 2 ( T3, N1, M1). Will it be the same as the specimen after the surgery? Can biopsy show distant metastasis? And lump node? Please advise. ... Read Full »
Answer: Hi, Welcome to icliniq.com. I understand your concern. I have seen the attached reports (attachments removed to protect the patient's identity). The Nottingham scale is used to classify the grade of the tumor. A score is given according to histology. The higher the score, the poor is differentiat... Read Full »
Query: Hello doctor, I have multiple problems with my stomach, it all began two years ago after taking pills which I was allergic to. My stomach became inflamed with a lot of acids, chronic antrum gastritis, and acid reflux. My stool was too soft, and I did not take any pill because my doctor did not give... Read Full »
Answer: Hi, Welcome to icliniq.com. All the problems can be explained by dyspepsia. Although there are certain issues like normal endoscopy and absence of inflammation. And on endoscopy reports (attachment removed to protect patient identity), there is no obvious granulation tissue seen. There may be s... Read Full »
I had a little scar on my thigh from squeezing a blackhead or a mole that caused brown discoloration. Can it be an early melanoma?
Query: Hello doctor, I had a little scar on my thigh from squeezing a blackhead or a mole eleven months ago. Now l have brown discoloration around the scar, which I am quite conscious about. I have two questions; 1) Could the slow healing be a sign that the blackhead was a black mole and resulted in an ear... Read Full »
Answer: Hello, Welcome to icliniq.com. From the attachment (attachment removed to protect the patient's identity), it does not seem anything more than just discoloration. Your doctor would have evaluated you in person and noted the size, shape, elevation, and surrounding area before advising you with a bi... Read Full »
Tests for stomach pain revealed a high eosinophil count. What to do?
Query: Hi doctor, I have a stomach ache from the last two months. It got worsened last week and I was admitted to a hospital. A lot of tests were done. The CBC revealed eosinophilia. The gastroscopy revealed an edematous duodenum. A duodenal biopsy was taken. I have attached my biopsy report. I want to u... Read Full »
Answer: Hello, Welcome to icliniq.com. I reviewed your biopsy report (attachment removed to protect patient identity), and the findings were normal. There is nothing to be worried about. You will need to use PPI's (proton pump inhibitors) to improve your symptoms. Regarding your eosinophilia, it ... Read Full »
Is a biopsy report essential when Corhn's signs are present during an abdominal surgery?
Query: Hello doctor, I had small bowel obstruction on the twenty-seventh of last month. They took out the appendix and attached fat tissue. They also found fluid in the stomach pelvis and cul-de-sac. I have lived with really bad constipation for some time tried everything to decrease it. I also have been ... Read Full »
Answer: Hello, Welcome to icliniq.com. I understand your concern and will help you regarding it. I have assessed the attachments thoroughly (attachments removed to protect the patient's identity). The histopathology report mentions in interpretation, "Appendicular mucosa with minimal focal acute inflammat... Read Full »
What are the risks of conducting biopsy on a pregnant woman?
Query: Hi doctor, I am 30 years old and 20 weeks pregnant. I got an abnormal pap result with ASC-H. I had another pap two years ago and it was normal. My doctor wants to do a colposcopy and biopsy. However, I read that it does result in complication when biopsy is performed on a pregnant woman. Can I do bi... Read Full »
Answer: Hi, Welcome to icliniq.com. I can understand your situation and concern. You have to undergo colposcopy and if necessary biopsy too. It can be done during pregnancy and the only problem may happen is mild bleeding, which can be managed. If the lesion is mild, then it can be followed up. Moder... Read Full »
I have seizures, balance, and memory issues, for which I got a brain biopsy. Please interpret the report.
Query: Hello doctor, I have had balance and memory issues for about a year, and my seizures started two months back. I had a brain biopsy done, for which the results have come, and I would like to have some information about what it means. Currently, I am taking anti-seizure, gout, and cholesterol medicati... Read Full »
Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. Your report (attachment removed to protect the patient's identity) shows a large brain tumor (glioma), one of the most common brain tumors in this age group. The tumor is associated with some bleeding foci, which im... Read Full »
What are the chances for my daughter to survive with multiple tumors and pericardial effusion?
Query: Hello doctor,My daughter is in the ICU with pericardial effusion and multiple tumors. The fluid has been drained and there was blood mixed with the fluid. The regular blood test came back normal with no sign of cancerous cells. My question is, what are the chances that the tumors are benign? Through... Read Full »
Answer: Hello, Welcome to icliniq.com. Firstly, there is a diagnostic dilemma. The reports you have uploaded (attachment removed to protect patient identity) are fine. But, you should upload the echo reports and the fluid investigations as well. Now, considering the pericardial effusion with multiple cardi... Read Full »
My mother had undergone laparotomy. Please advice on her biopsy reports.
Query: Hello doctor,My mother has been operated two months before. She was suffering from constipation, and the doctor found a tumor in the CT scan. Some operation called laparotomy was done. After that, she is fine now. The stool is passing through the stoma. After the biopsy report, I have been asked to ... Read Full »
Answer: Hello, Welcome to icliniq.com. So she has colonic carcinoma. As you told, she is passing stool through the stoma, that gives me the impression that probably she was not surgically fit at the time of surgery to complete operation in one stage. As per the cancer stage, she needs to undergo cancer chem... Read Full »
My biopsy report showed granulomatous mastitis. Was the biopsy specimen autolyzed?
Query: Hi doctor, A wide excision was done last year, and the report showed granulomatous mastitis. How can autolyzed tissue alter the report of biopsy? What do you mean by autolysis? What if the specimen is autolyzed? What would you do? Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hi, Welcome to icliniq.com. Autolysis means self-digestion of tissue by our own enzymes. To prevent autolysis, the specimen should be transferred to 10 % buffered formalin immediately after tissue removal by a surgeon. Formalin fixes the tissue and prevents autolysis, so that tissue preserved in... Read Full »