Can Semaglutide impact the treatment of bipolar disorder?

Question

Hello Doctor,

I am 36 years old and have been diagnosed with bipolar disorder type 2. I am currently taking Iamotrigine and Bupropion. Eight weeks ago, I began taking compounded Semaglutide for weight loss. I have lost 25 pounds so far, but I have started experiencing increased anxiety, panic attacks, and mood swings. My sleep has also been disrupted by vivid nightmares.

My psychiatrist is not familiar with Semaglutide or how it might interact with my current psychiatric medications. Could this medication be triggering mood episodes or interacting with my treatment? Is it safe to continue both Semaglutide and my psychiatric medications together? What kind of monitoring should I request?

I would appreciate some practical advice on how to manage my mental health while taking medication for weight loss.

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

The bipolar significant seventh chapter in the new edition of Take Charge of bipolar disorder explains why people with bipolar disorder need a plan when using any substance that affects the brain.

It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.

Healthcare professionals should be aware of the potential for adverse psychiatric events, particularly depression, anxiety, and suicidal ideation, associated with Semaglutide(GLP-1 receptor agonists).

I hope I answered your query.

Thank you.