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What impact does Lorazepam withdrawal have on bipolar disorder?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been taking 1.5 mg of Ativan for five years. I have bipolar 1, and it is the only medication that helps me sleep. They have tried everything on me. I would like to stop taking it, but I am very afraid of the insomnia and mania that might follow. I have also heard that the withdrawal is awful! I am wondering if I can work on lowering my dose. I would be working with my doctor, who is weighing the risks and benefits. I am on Lamotrigine and 1.25 to 1.5 mg of Ativan. I worry about dementia, and she is concerned about taking me off it. I just wanted a different opinion.

Please guide.

Thank you.

Answered by Dr. Vipul Chelabhai Prajapati

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

As you have bipolar disorder (Mental illness with alternating episodes of mania and depression, affecting mood and energy levels), you can gradually quit Ativan (Lorazepam, an anti-anxiety drug). At a dose of 1.25 to 1.5 mg, there should not be any major memory problems. You can gradually reduce the dosage while maintaining good sleep hygiene. You can also consider gradually shifting to melatonin.

The main thing is to maintain good sleep hygiene, which includes daily exercise, avoiding smoking and drinking, avoiding tea and coffee, and taking hot milk. Do not worry about dementia at this dose. You can start another mood stabilizer like Olanzapine or Divalproate.

I hope this information helps you, and please reach out if you have any doubts.

Thank you.

Medically reviewed by iCliniq medical review team
Published At March 24, 2025
Reviewed At March 24, 2025

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

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