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What are the ways to manage chronic migraine in a woman?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 38-year-old woman who has been experiencing migraines for several years. My doctor recently recommended monthly injections to help prevent them, but I am a bit concerned about potential side effects and the overall cost.

  1. How effective are these injections compared to oral medications? Are they meant to be taken indefinitely, or is it possible for migraines to improve with age?

  2. I have also noticed that my migraines tend to worsen around my menstrual cycle. Could this indicate a hormonal trigger?

  3. I would like to know whether these injections are considered safe for women who may plan to become pregnant in the future.

Please help.

Thank you.

Answered by Dr. Prakashkumar P Bhatt

Education:

MBBS

Professional Bio:

Dr. Prakashkumar P. Bhatt is a dedicated Neurologist committed to providing comprehensive care for patients with neurological conditions. He is skilled in diagnosing and managing a wide range of disorders, combining clinical expertise with a compassionate approach to treatment. Known for his clear communication and patient-centered care, Dr. Bhatt focuses on creating personalized treatment plans that support better health outcomes and improved quality of life.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Your concerns are completely understandable, and it is great that you are taking the time to learn more. Let us go through each point clearly:

About the injections: The monthly injections your doctor mentioned are called CGRP monoclonal antibodies (such as Erenumab, Fremanezumab, Galcanezumab, or Eptinezumab). These medications are designed to prevent migraines rather than treat them once they begin.

Effectiveness: Studies show that these injections can reduce the number of migraine days by about 50–70% in many people, particularly in those who have not responded well to oral preventive medicines like Propranolol, Topiramate, or Amitriptyline. They also tend to act more quickly and usually cause fewer side effects, such as fatigue or weight changes.

Duration of use: You do not necessarily need to take them indefinitely. Doctors often recommend trying them for six to 12 months. If your migraines remain well controlled, the treatment interval may be extended or paused under medical supervision.

Hormonal connection: It is quite common for migraines to worsen around your menstrual period due to a sudden drop in estrogen levels. This is known as menstrual migraine. Tracking your cycle can help identify these patterns, and in some cases, short-term preventive therapy around your period can be helpful.

Pregnancy considerations: CGRP monoclonal antibodies are not currently recommended during pregnancy, as there is not enough safety data yet. If you are planning to conceive soon, your doctor may suggest other preventive options for now, with the possibility of trying these injections later.

These treatments are generally effective and well-tolerated, and they can make a big difference in quality of life. However, it is important to discuss the potential costs and your future pregnancy plans with your neurologist before starting therapy.

I hope this helps.

Kindly revert if there are any queries.

Thank you.

Medically reviewed by iCliniq medical review team
Published At January 8, 2026
Reviewed At January 9, 2026

Education:

MBBS

Professional Bio:

Dr. Prakashkumar P. Bhatt is a dedicated Neurologist committed to providing comprehensive care for patients with neurological conditions. He is skilled in diagnosing and managing a wide range of disorders, combining clinical expertise with a compassionate approach to treatment. Known for his clear communication and patient-centered care, Dr. Bhatt focuses on creating personalized treatment plans that support better health outcomes and improved quality of life.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Prakashkumar P. Bhatt is a dedicated Neurologist committed to providing comprehensive care for patients with neurological conditions. He is skilled in diagnosing and managing a wide range of disorders, combining clinical expertise with a compassionate approach to treatment. Known for his clear communication and patient-centered care, Dr. Bhatt focuses on creating personalized treatment plans that support better health outcomes and improved quality of life.

This doctor is not available for online consultations on the platform anymore.

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