Co2 Infusion

Carbon dioxide infusion therapy is a procedure used in chronic wounds in lower limbs or chronic ulcers with venous insufficiency to achieve tissue oxygenation for effective healing. The carbon dioxide is infused transdermal, percutaneous, and subcutaneously to restore the blood flow in long-standing wound areas' microcirculation. Due to an increase in carbon dioxide concentrations, the pH decreases. As a result, the nitric oxide gets activated and induces vascular endothelial and fibroblast growth factors and the formation of collateral vessels. Efficient blood flow in the microcirculation with tissue oxygenation aid in healing.