Do Indomethacin and Misoprostol contain the same ingredients as Celebrex?

Question

Hello doctor,

I am allergic to Celebrex, as it causes me hypertension and chest pains when I take it. After undergoing hip surgery recently, my doctor prescribed Indomethacin and Misoprostol as substitutes for Celebrex. However, I have started experiencing the same side effects with these two drugs as I did with Celebrex, including extreme anxiety, confusion, and hypertension. A pharmacist informed me that Indomethacin and Misoprostol are the same drugs found in Celebrex, suggesting that there may have been an error in prescribing them to me. I shared this information with my family doctor, but they did not believe that information to be true. Now, I am feeling afraid and uncertain. Should I continue taking the prescribed drugs as advised by my doctor or should I stop taking them? My question is, is Indomethacin and Misoprostol combination the same drugs as those found in Celebrex, as the pharmacist informed me?

Kindly suggest.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and understood your concern. I would like to inform you that Celebrex (nonsteroidal anti-inflammatory drug) contains Celecoxib, whereas as you mentioned, you have been prescribed Indomethacin (nonsteroidal anti-inflammatory drug) and Misoprostol (pPostaglandin E1 analog) as a replacement. Therefore, there should be no doubt about their composition. Secondly, if you are experiencing the same side effects from Indomethacin and Misoprostol, I suggest you consult your doctor in person. They can determine whether these side effects are certainly caused by the medication or if there might be another underlying issue. I hope this has helped you. Kindly follow up if you have more doubts.

Thank you.