Common "Her2" queries answered by top doctors | iCliniq


Human epidermal growth factor receptor 2 (HER2) is a gene that plays a significant part in the growth of breast cancer. HER2 genes are responsible for producing HER2 proteins, which helps in cell production, division, and repair. However, in some cases, these genes replicate and cause overexpression of HER2 protein, resulting in uncontrolled cell growth and division. As a result, HER2 positive breast cancer comparatively grows faster than HER2 negative breast cancer, diagnosed by immunohistochemistry (IHC) test and fluorescence in situ hybridization (FISH) test.

Recently Answered Questions Recently Answered Questions

All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Could you please explain HER2-positive breast cancer?

Query: Hello doctor, We recently found out that my mom has HER2-positive breast cancer, and I am a bit overwhelmed by all the information out there. I have heard about HER2, but I am not entirely sure what it means for my diagnosis and treatment. Could you please explain what HER2-positive breast cancer i...  Read Full »

Dr. Arshad Hussain Shah

Answer: Hello, I am glad you chose icliniq for your medical-related queries. I can understand your concern. HER2-positive breast cancer is a type of breast cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2). This protein promotes the growth of cancer cells. In...  Read Full »

Would I need HER2 injections after chemo and radiation therapy?

Query: Hello doctor, For a person who has completed six chemotherapy sessions and month-long radiation for breast cancer treatment, how many HER2 injections are required after the above? ERPR/HER2 parameters are negative.  Read Full »

Dr. Pawar Satyajit Jalinder

Answer: Hello, Welcome to Can you give information regarding a few details? What was the stage? What was the histopathology report? What chemotherapy was received? If ER/PR and HER 2 was negative, then was FISH (fluorescence in-situ hybridization) done? If HER 2 is negative by FISH and histo...  Read Full »

My mother has breast cancer. What treatment can she take?

Query: Hello doctor, I need advise from experts about my mother. She is suffering from breast cancer. It was diagnosed two days ago. I want an expert's opinion for future treatment. Kindly guide me. What is the best treatment?  Read Full »

Dr. Arshad Hussain Shah

Answer: Hello, Welcome to I have gone through the attached reports (attachment removed to protect patient identity). Yes, the biopsy report has confirmed the diagnosis of breast cancer. Now, the next step will be to stage this disease. For that purpose, she will be adviced to do a CT scan of ...  Read Full »

I have breast cancer. Will taking Pembrolizumab help?

Query: Hi doctor, I am a 40-year-old woman recently diagnosed with breast cancer, and it has been hard, especially considering I have a 5-year-old child. I have been feeling quite depressed about the situation. I was wondering if Keytruda, a medication I have heard of, could assist with my particular situ...  Read Full »

Dr. Arshad Hussain Shah

Answer: Hello, Welcome to I have read your query, and I can understand your concern. Keytruda (Pembrolizumab) is an immunotherapy drug and is usually not used in all types of breast cancer. It can be used in a subtype of breast cancer called triple-negative breast cancer with PD L1 (programm...  Read Full »

I am a 53-year-old postmenopausal female and I have been recently diagnosed with invasive ductal carcinoma of the right breast. Please help.

Query: Hi doctor, I am a 53-year-old postmenopausal female and I have been recently diagnosed with ER, PR, and HER2 positive invasive ductal carcinoma of the right breast. Please help.  Read Full »

Dr. Jacqueline F. Bromberg

Answer: Hi, Welcome to With passion, commitment and experience, I hope I will be able to provide you with top class medical opinion. I can infer that you are a 53-year-old post-menopausal woman diagnosed with screen-detected invasive ductal carcinoma. From your reports (attachments removed t...  Read Full »

What tests are recommended to determine the type of treatment for breast cancer?

Query: Hi doctor, My mother is diagnosed with breast cancer, and there is pain in her left breast, waist, and back. Can you please tell me the treatment options available?  Read Full »

Dr. Pawar Satyajit Jalinder

Answer: Hello, Welcome to I have gone through your query and the reports (attachment removed to protect the patient's identity) you have provided. I can understand that this would be a difficult time for your family, and it is natural to get a second opinion. Based on reports, it looks...  Read Full »

Is my mother's breast cancer treatment correct?

Query: Hi doctor, My mother, who is 55 years old, is undergoing chemotherapy for breast cancer T4 M1 (less than 5 mm non-avid in lymph node above lung) Nx, after mastectomy. She is HER2 positive and other two receptors are also positive. We have two different opinions in front of us from the two best onco...  Read Full »

Dr. Bharat Patodiya

Answer: Hi, Welcome to I understand your plight. Your mother seems to be in stage 4 and less likely 3. However, to give the benefit of doubt, I think that people has considered to give chemotherapy followed by response evaluation. If the result is favorable, then they may even opt for surger...  Read Full »

Is it necessary to remove the entire breast in case of cancer?

Query: Hi doctor, My mother-in-law got operated for breast lump at before 15 days. We sent that lump to the clinic for further test and found that the lump has cancer cells. Before 13 years, she was operated for the same reason in the same breast, but that time it was a normal lump. Now, we did PET CT scan...  Read Full »

Dr. Bharat Patodiya

Answer: Hello, Welcome to I could not find hormone status and HER2 report. Is it done and awaited? The decision of chemotherapy is greatly influenced by those reports. Moreover, the margin seems to be positive and this may need a revision surgery. The pathologist and surgeon needs to discuss. R...  Read Full »

ask-doctor-img Ask a Doctor Online

* Your first query consult is free!

Search for a Health Issue

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.