An immunogenic epitope is a part of the antigen that is recognized by the immune system, particularly by the antibodies, B cells, or T cells. It is also known as an antigenic determinant. There are different types of epitopes based on their structure and interactions.
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Query: Hello doctor, I have studied that Human Leukocyte antigen (HLA-B35, HLA-B58, and HLA-B7) are responsible for the rapid progression of AIDS (Acquired Immunodeficiency Syndrome) and often test false negative when tested. However, with C clade virus it is somewhat protective and does not lead to rapid ... Read Full »
Answer: Hello, Welcome to icliniq.com. Yes, HLA-B35/58 (human leukocyte antigen) person will be able to produce antibodies against HIV-1 (human immunodeficiency virus). This is true for all clades. The immunogenic response is known to be somewhat greater in clade C due to a higher diversity of immunogenic e... Read Full »