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Will an HLA-B35/58 person produce antibodies against HIV?
Query: Hello doctor, I have studied that HLA-B35, HLA-B58, and HLA-B7 are responsible for the rapid progression of AIDS and often test false negative when tested. However, with C clade virus it is somewhat protective and does not lead to rapid disease progression which has something to do with the CD8 T ce... Read Full »
Answer: Hello, Welcome to icliniq.com. Yes, HLA-B35/58 (human leukocyte antigen) person will be able to produce antibodies against HIV-1 (human immunodeficiency virus). This is true for all clades. The immunogenic response is known to be somewhat greater in clade C due to a higher diversity of im... Read Full »