Common "Immunogenicity" queries answered by top doctors | iCliniq


Immunogenicity refers to the ability of the foreign substance or therapeutic products to stimulate an immune response. Immunogenicity measures how well the vaccines work and the type of immune response the vaccine generates, and their magnitude over time.

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Can an HLA-B35/58 person produce antibodies against HIV?

Query: Hello doctor, I have studied that Human Leukocyte antigen (HLA-B35, HLA-B58, and HLA-B7) are responsible for the rapid progression of AIDS (Acquired Immunodeficiency Syndrome) and often test false negative when tested. However, with C clade virus it is somewhat protective and does not lead to rapid ...  Read Full »

Dr. Ravinder K. Sachdeva

Answer: Hello, Welcome to Yes, HLA-B35/58 (human leukocyte antigen) person will be able to produce antibodies against HIV-1 (human immunodeficiency virus). This is true for all clades. The immunogenic response is known to be somewhat greater in clade C due to a higher diversity of immunogenic e...  Read Full »

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