HomeAnswersMedical Gastroenterologyirritable bowel syndrome

I have IBS and changes in my stool. How can I manage it?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 29-year-old female, five feet three inches, 167 pounds, with a history of irritable bowel syndrome.

Over the past six months, I have experienced increased diarrhea with foul-smelling stools of varying colors (yellow, lime green, dark brown), abdominal and back pain, nausea, and fatigue, along with fluctuating weight.

My fecal occult blood test was negative, and liver ultrasound showed a 6.1-inch liver with a 0.55-inch echogenic nodule.

My current medications include Dextroamphetamine and Amphetamine extended-release 30 milligrams, Buspirone 10 milligrams, Lurasidone 20 milligrams, and Vybrid 10 milligrams.

Kindly help.

Answered by Dr. Ahsanullah Niazai

Education:

MD

Professional Bio:

Dr. Ahsanullah Niazai is a General Physician with a strong commitment to patient-centered care and medical education. He is skilled in diagnosing and managing a wide range of acute and chronic health conditions. His areas of expertise include internal medicine, preventive healthcare, and clinical education, with a focus on promoting overall well-being and disease prevention.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

Based on your ultrasound, your liver measures 6.1 inches, which is at the upper limit of normal and may suggest mild enlargement, particularly if you have a smaller body frame.

Within the liver, a 0.55-inch echogenic nodule was noted, which appears as a well-defined area reflecting more sound waves than the surrounding tissue.

Such nodules are often benign and may represent a hemangioma, which is a small collection of blood vessels, or a focal fatty deposit.

However, imaging alone cannot definitively determine its nature, and a contrast-enhanced liver magnetic resonance imaging (MRI) or computed tomography (CT) scan is recommended for a more accurate assessment.

In addition to the imaging findings, your ongoing symptoms, including foul-smelling diarrhea, stool color changes ranging from yellow to green, fatigue, and abdominal discomfort, suggest that there may be underlying issues beyond irritable bowel syndrome.

These changes can occur when bile moves too quickly through the intestines or when fat digestion is impaired, which can point toward bile flow disturbances, pancreatic insufficiency, or malabsorption.

Since your fecal occult blood test was negative, gastrointestinal bleeding is unlikely, but further stool studies, such as fecal fat analysis, calprotectin, and stool elastase, can help evaluate inflammation or pancreatic function.

It is also important to check liver function tests, bilirubin, alkaline phosphatase, and possibly celiac antibodies to rule out other digestive or liver-related conditions.

I hope this information helps you.

Thank you.

Medically reviewed by iCliniq medical review team
Published At December 23, 2025
Reviewed At December 24, 2025

Education:

MD

Professional Bio:

Dr. Ahsanullah Niazai is a General Physician with a strong commitment to patient-centered care and medical education. He is skilled in diagnosing and managing a wide range of acute and chronic health conditions. His areas of expertise include internal medicine, preventive healthcare, and clinical education, with a focus on promoting overall well-being and disease prevention.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

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Companion

IBS with Liver Nodule Companion

How it works

You're experiencing new or worsening symptoms with IBS, including changes in your stool and liver findings. This companion helps you understand these issues and prepare for a doctor's visit.

1

Your
Symptoms

2

Liver
Ultrasound

3

Nodule
Interpretation

4

Underlying
Causes

5

Stool
Tests

6

Blood
Tests

Important Note on Medications

Medications should be taken after consulting a physician. The dosages will be prescribed by the physician. Do not alter, start, or stop medications without consulting a healthcare professional. Your current medications (Dextroamphetamine and Amphetamine extended-release, Buspirone, Lurasidone, and Vybrid) should be discussed with your doctor regarding any potential interactions or effects on your symptoms.

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Education:

MD

Professional Bio:

Dr. Ahsanullah Niazai is a General Physician with a strong commitment to patient-centered care and medical education. He is skilled in diagnosing and managing a wide range of acute and chronic health conditions. His areas of expertise include internal medicine, preventive healthcare, and clinical education, with a focus on promoting overall well-being and disease prevention.

This doctor is not available for online consultations on the platform anymore.

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