Is Erenumab effective for my frequently occurring migraines?

Question

Hello doctor,

I have had migraines since I was a teen, but they are getting worse lately, sometimes 15 to 20 days a month. I heard about medications like Erenumab,

Are they better than triptans or just used when those fail?
Are there any risks with long-term use of these medications?
I also want to know if hormonal migraines are treated differently?
I am tired of missing work from all the pain and nausea.

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com

I read your query and understand your concern.

Living with frequent migraines, especially at the intensity and frequency you describe, can be truly debilitating.

CGRP (calcitonin gene-related peptide) monoclonal antibodies, such as Erenumab, are part of a newer class of preventive migraine therapies. They work differently from triptans, which are typically used to abort a migraine attack once it begins. CGRP blockers are used to reduce the frequency and severity of migraines, especially in patients like you who experience chronic migraines (more than 15 days per month). Common side effects may include constipation or injection site reactions. Serious side effects are rare. Regular follow-up is important, but many patients find significant relief with minimal adverse effects.

Hormonal migraines, often linked to menstrual cycles, can require specific strategies, including:

Short-term preventive use of NSAIDs (nonsteroidal anti-inflammatory drugs) or triptans around the menstrual period. Some patients with both hormonal and chronic migraines benefit from combining these strategies with CGRP blockers or other preventive treatments like Topiramate or beta blockers.

A detailed menstrual and migraine diary can help identify patterns and tailor your treatment accordingly. You are not alone in this, and effective relief is possible. Together, we can develop a treatment plan that helps you regain control and reduce the toll migraines are taking on your work and well-being.

I hope this helps.

Thank you.