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What causes recurrent miscarriages and preterm labor?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I had two miscarriages in the fifth month of pregnancy. In my last pregnancy, I had cerclage stitches. However, the waterbag leaked at the end of the fifth month, and the pain started. The doctors had to open the stitches and deliver the baby as a normal delivery. What could be the reason for my miscarriages?

Kindly help.

Answered by Dr. Uzma Arqam

Hello,

Welcome to icliniq.com.

Thank you for your query.

I understand your concern. You have had two miscarriages and one preterm labor with cerclage stitches and cervical incompetence. Three or more consecutive pregnancy loss is known as recurrent miscarriage. These can occur due to the following causes:

  1. Epidemiological factors such as advanced maternal or paternal age, maternal smoking and caffeine, heavy alcohol consumption, and obesity.
  2. Antiphospholipid syndrome, in which certain antibodies such as lupus anticoagulant, anticardiolipin antibody, and glycoprotein antibody can cause abnormal thrombosis and pregnancy outcome.
  3. Genetic factors and congenital chromosomal abnormalities.
  4. Anatomical factors such as uterine malformation and cervical weakness.
  5. Endocrine problems such as diabetes, thyroid problems, and polycystic ovarian syndrome.
  6. Immune-related factors such as cytokine polymorphisms.
  7. Infective causes such as TORCH (toxoplasma gondii, other agents (treponema pallidum, varicella-zoster virus, parvovirus B19, and human immunodeficiency virus), rubella, cytomegalovirus, and herpes simplex virus and bacterial vaginosis.
  8. Inherited factors such as inherited thrombophilic defects.

I suggest you to follow a few instructions mentioned below.

  1. Visit a specialist and undergo detailed examination and investigations to find out the underlying cause of the issue.
  2. Initiate treatment for the underlying problem to ensure a healthy full-term pregnancy next time.
  3. Undergo specific investigations six to eight hours post-miscarriage.
  4. Undergo the thrombophilia screening now if it has been six weeks post-delivery or miscarriage.
  5. Take folic acid supplements daily.
  6. Have a balanced and nutritious diet.
  7. Maintain a healthy BMI (body mass index).
  8. Exercise regularly.
  9. Do yoga.
  10. Quit smoking, alcohol, and recreational drugs.

I hope this has helped you. Thank you.

Answered byDr. Uzma Arqam

Medically reviewed byiCliniq medical review team

Published At December 23, 2022
Reviewed AtMay 5, 2026

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Uzma Arqam
Dr. Uzma Arqam

Obstetrics and Gynecology

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