Is Zejula 200 mg safe for the liver in hepatitis?

Question

Hello doctor,

I am a woman managing ovarian cancer and currently taking Zejula 200 mg daily after food at the same time as advised by my doctor. I have concerns regarding its interaction with my hepatitis condition. I asked my doctor about this, and he said the dosage is correct for my weight of 154 pounds, and this is a minimal dose and will not harm my liver. But my doubt is still there.

Could you please provide detailed information about the side effects or risks associated with Zejula in someone with hepatitis?
How will this medicine impact my liver function, and are there specific tests we should consider?
Are there any precautions, dosage adjustments, or additional supportive measures I should take to reduce side effects?

Please help.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query, and I can understand your concern.

Zejula tablets, or Niraparib are less toxic to the liver, but as you have a preexisting liver condition, you just need to monitor an LFT (liver function test) and the blood test, including liver enzymes, every month. The common side effects of Zejula are low blood counts, loose motions, decreased appetite, constipation, high blood pressure, and skin conditions. As you are taking low-dose Zejula, it will be unlikely to cause any hepatic toxicity, unless the liver is severely damaged.

I hope I have cleared up all your doubts.