Prostate-specific Antigen

Prostate-specific antigen (PSA) is a substance produced by both normal and malignant cells of the prostate. The PSA test measures the amount of PSA in a men's blood. The normal value of PSA ranges from 0.0 to 2.5 ng/mL. It varies according to the age of the males. A range of 4.0 to 10.0 ng/mL suggests the possibility of a twenty-five percent chance of having prostate cancer. Having a range above 10.0 ng/mL means a fifty percent chance of having prostate cancer.

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I recently had an MRI of my prostate gland due to variations in PSA scores. What does the report suggest about my prostate gland?

Query: Hello doctor,I just recently had MRI. I wanted to get your opinion on it. I am a 52-year-old with a genetic father who died of prostate cancer. My PSA scores have ranged from as high as 3 to as low as 2 in the past couple of years. My most recent PSA test was about a month ago and showed a reading o...  Read Full »

Dr. Andrew Chellakumar Fenn

Answer: Hi, Welcome to I understand your concern. I will get back to you. I am unable to open the files you attached. I have asked for technical support. In the meanwhile, if you could resend the files or re-attach them, as well as contact support, it would be a great help. Sorry for the incon...  Read Full »

Does a high PSA level warrant a biopsy?

Query: Hi doctor, I am 62 years old. I have severe pain while urinating and having frequent urination at night. My PSA 62.32, prostate 78 g, RUV 142 mL. Should I get a biopsy?  Read Full »

Dr. Gupta Aman Manoharlal

Answer: Hi, Welcome to I hope your doctor has examined you physically. If there is a doubt of any tumor on prostate examination, then a biopsy should be done. If there is any history of a recent proven urinary tract infection in the last few days, then PSA (prostate-specific antigen)...  Read Full »

Is surgery needed for my prostate cancer?

Query: Hi doctor, I am on active surveillance for the last 2 years. My initial prostate biopsy was 2 years ago and showed 1 out of 10 needles cancerous, Gleason 6, slow growing and Prolaris test showing a medium growth rate. I had second biopsy 6 months ago. Before the second biopsy, my PSA was 5 and four ...  Read Full »

Dr. Khant Shahil Ramesh Bhai

Answer: Hi, Welcome to I have gone through your details. My main concern is the rise of PSA (prostate-specific antigen) from 5 to 16.Though it might be due to infection, since three months you are taking treatment of infections. So, your PSA should have reduced if the rise was due to infection....  Read Full »

My father has a third-degree prostatomegaly with a decreased PSA. What to do?

Query: Hello doctor, This query is regarding my father. He is 65 years old. He suffers from BPH from the last five years and takes Alfusin-D for the same. Five years back, when he was diagnosed, his PSA was 2.8 ng. Last year, we repeated his test and the PSA was 0.9 ng/ml with normal DRE. An ultrasound of ...  Read Full »

Dr. Choudhary Devendra

Answer: Hello, Welcome to The PSA (prostate-specific antigen) has decreased due to Dutasteride component of Alfusin-D. I suggest he get the screening done yearly for a year or two. Then, a two-yearly screening of PSA and DRE (digital rectal examination) is alright as his PSA is low in spite...  Read Full »

Is the rise in PSA value related to hemorrhoid vein thrombosis?

Query: Hi doctor, My query is related to PSA values. Please look into the attachment. The person is currently suffering from a thrombosed hemorrhoid vein. The treatment which the doctor has proposed is Movicol a stool softener once daily, Daflon thice daily for the first four days and afterwards for three ...  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hi, Welcome to I have thoroughly gone through your case and can well understand your genuine health concerns.  Read Full »

I think cancer has spread because my PSA levels are doubling every six months. Will castration help me?

Query: Hello doctor, My PSA levels are increasing despite having had a prostatectomy two years ago. My PSA levels are doubling every six months. It is not yet at a serious level, but I think cancer has spread. Should I undergo castration to overcome this problem? Thank you.  Read Full »

Dr. Samer Sameer Juma Ali Altawil

Answer: Hello,Welcome to surgery, PSA (prostate-specific antigen) levels above 0.1 ng per mL are considered high and need further evaluation with a PET (positron emission tomography) scan. If local reoccurrence occurs, radiation is the treatment option. If it is out of the prostate gland, ...  Read Full »

I was advised medicines after a routine prostate test, but I have no symptoms. Please suggest.

Query: Hello doctor, I am a 66 year old male. My only medical history is hypertension (controlled) with Norvasc. I went for my routine prostate test a couple of months ago and the result stated: PSA - 9.8 ng/mL. Free PSA - 1.9 ng/mL. Percentage free PSA - 19.4 %. I went back to another doctor a few weeks a...  Read Full »

Dr. Sandhya Narayanan Kutty

Answer: Hello, Welcome to After analysis of the history provided, I would like to give you a brief idea of the same. Firstly PSA (prostate-specific antigen) varies with age. As the age advances, it keeps increasing.Secondly, in spite of that, the PSA level mentioned in your report is in a highe...  Read Full »

My father is 85-year-old and has been diagnosed with prostatic adenocarcinoma. What could be done?

Query: Hello doctor, My 85-year-old father has been diagnosed with prostatic adenocarcinoma. His biopsy reports show Gleason's grade 3+4 (percentage of grade 4 is 30 %), tumor involves 60 % of submitted biopsy. No perineural invasion is seen. His PSA level is 107.69 ng/mL. He has triple vessel heart diseas...  Read Full »

Dr. Bharat Patodiya

Answer: Hello, Welcome to You can get a staging workup with PSMA (prostate-specific membrane antigen) scan or bone scan and MRI (magnetic resonance imaging) pelvis. His high PSA (prostate-specific antigen) does make him a high risk but considering his age. I will not suggest a very aggressive a...  Read Full »

What is the cause of high levels of prostate antigen test?

Query: Hello doctor,I got my father's prostate antigen test results today. It was 10.59 ng/mL. I am worried if it shows the beginning of prostate cancer. But, there are no specific complaints. Sometimes, he has a delay in urinating and little pain on urinating, and puss is found in urine. Currently, he is ...  Read Full »

Dr. Samer Sameer Juma Ali Altawil

Answer: Hello, Welcome to PSA (Prostate-specific antigen test) is prostate-specific but not cancer-specific, and it requires careful clinical evaluation. First, check digital rectal examination, and after exclusion of infection or prostatitis and treatment with antibiotics, repeat it. Then, I...  Read Full »

Can Septrin forte be taken for prostate infection?

Query: Hi doctor, I have Morganella morganii infection in the prostate. For the past 15 years, I have been getting blood in semen. I had a short course of antibiotics in the past and I also had a semen microbiological test. Please recommend some antibiotics.  Read Full »

Dr. Raman Tanwar

Answer: Hi, Welcome to For the infection in the prostate a four to six weeks course of treatment is highly recommended. I suggest Cephalosporins and Aminoglycosides are the best for initial therapy, but ideally it should be guided by culture sensitivity reports. Consult your specialist doctor,...  Read Full »

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