Common "Prostate-specific Antigen" queries answered by top doctors | iCliniq

Prostate-specific Antigen

Prostate-specific antigen (PSA) is a substance produced by both normal and malignant cells of the prostate. The PSA test measures the amount of PSA in a men's blood. The normal value of PSA ranges from 0.0 to 2.5 ng/mL. It varies according to the age of the males. A range of 4.0 to 10.0 ng/mL suggests the possibility of a twenty-five percent chance of having prostate cancer. Having a range above 10.0 ng/mL means a fifty percent chance of having prostate cancer.

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My PSA levels increased despite the prostatectomy. Why?

Query: Hello doctor, My PSA levels are increasing despite having had a prostatectomy two years ago. My PSA levels are doubling every six months. It is not yet at a serious level, but I think cancer has spread. Should I undergo castration to overcome this problem? Thank you.  Read Full »

Dr. Samer Sameer Juma Ali Altawil

Answer: Hello,Welcome to surgery, PSA (prostate-specific antigen) levels above 0.1 ng per mL are considered high and need further evaluation with a PET (positron emission tomography) scan. If local reoccurrence occurs, radiation is the treatment option. If it is out of the prostate gland, ...  Read Full »

My father is 85-year-old and has been diagnosed with prostatic adenocarcinoma. What could be done?

Query: Hello doctor, My 85-year-old father has been diagnosed with prostatic adenocarcinoma. His biopsy reports show Gleason's grade 3+4 (percentage of grade 4 is 30 %), tumor involves 60 % of submitted biopsy. No perineural invasion is seen. His PSA level is 107.69 ng/mL. He has triple vessel heart diseas...  Read Full »

Dr. Bharat Patodiya

Answer: Hello, Welcome to You can get a staging workup with PSMA (prostate-specific membrane antigen) scan or bone scan and MRI (magnetic resonance imaging) pelvis. His high PSA (prostate-specific antigen) does make him a high risk but considering his age. I will not suggest a very aggressive a...  Read Full »

Why was Finasteride prescribed despite no urinary symptoms?

Query: Hello doctor, I am a 66-year-old male. My only medical history is hypertension (controlled) with Norvasc. I went for my routine prostate test a couple of months ago and the result stated: 1. PSA - 9.8 ng/mL. 2. Free PSA - 1.9 ng/mL. 3. Percentage free PSA - 19.4 %. I went back to another doctor a f...  Read Full »

Dr. Sandhya Narayanan Kutty

Answer: Hello, Welcome to After analysis of the history provided, I would like to give you a brief idea of the same. Firstly PSA (prostate-specific antigen) varies with age. As the age advances, it keeps increasing. Secondly, in spite of that, the PSA level mentioned in your report is in a...  Read Full »

Can a PSA value rise relate to hemorrhoid vein thrombosis?

Query: Hi doctor, My query is related to PSA values. Please look into the attachment. The person is currently suffering from a thrombosed hemorrhoid vein. The treatment which the doctor has proposed is Movicol, a stool softener once daily, Daflon thice daily for the first four days and afterwards for three...  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hi, Welcome to I have thoroughly gone through your case and can well understand your genuine health concerns. I will try to remain as simple as possible in my conversation so that everything is pretty much clear and easy understandable to you. I have seen the prostate-specific antigen ...  Read Full »

I was diagnosed with Gleason 6 and PSA levels are rising. Why?

Query: Hello doctor, I was diagnosed with Gleason 6 before twelve years. Undergoing radiotherapy from then, intially, it was 0.40 nadir, which increased annually. The last four PSA readings were 1.12 ng/mL, 1.60 ng/mL, 1.46 ng/mL, and 2.35 ng/mL. This last value was my concern. My urologist has retired, an...  Read Full »

Dr. Saurabh Subhash Pandya

Answer: Hello, Welcome to Your PSA (prostate-specific antigen) has been rising post-radiotherapy. Since it is above 2.0 ng/mL, I suggest you go for a PSMA PET (prostrate-specific membrane antigen positron emission tomography) scan. This will show any recurrence in the prostate or lymph nodes ...  Read Full »

Old male with IgA nephropathy, hypertension. Is total PSA rise?

Query: Hi doctor, I am a 62-year-old male and have had IgA (immunoglobulin A) nephropathy and hypertension for the past 11 years, which is being treated with Cardace 10 mg, Stamlo 5 mg, Lipitor 10 mg, and fish oil capsules. In addition, I have thyroid nodules (no medication). BP is around 130/80. I have h...  Read Full »

Dr. Samer Sameer Juma Ali Altawil

Answer: Hi, Welcome to I understand your concern. There is no relationship between Urimax and PSA (prostate-specific antigen) level. There are fluctuations in the PSA in this range which is normal, and any PSA above 1.4 should be repeated twice yearly. If we notice two consecutive rises in P...  Read Full »

My PSA is 7.1 ng/ml, and I have frequent urge to urinate. Can sex increase the PSA value?

Query: Hi doctor, I am a 52-year-old male. I took blood tests a few months back. My cholesterol level was high, and the PSA was 1.0 ng/ml. I am taking a tablet of Rosuvastatin for the last five months for high cholesterol. Recently, I took blood tests, and my cholesterol levels were normal, but my PSA was...  Read Full »

Dr. Madhav Tiwari

Answer: Hello, Welcome to I understand your concern. An increase in the PSA (prostate-specific antigen) level can be due to various reasons including, urinary tract infection, excess long-distance cycling, recent instrumentation of your urethra, prostatic infection, prostate cancer, benign pr...  Read Full »

I am a 31-year-old male, experiencing high PSA (9.95) and occasional frequent urination for one year now. Is this due to a kidney infection?

Query: Hello doctor, I am a 31-year-old male with a normal BMI, and no other known health issues, non-smoker, non-drinker, and no drug use ever. My appendix got removed 10 years ago. I have been experiencing high PSA and occasional frequent urination for one year now. The latest total PSA is 9.95. Urine...  Read Full »

Dr. Tuljapure Samit Prabhakarrao

Answer: Hello, Welcome to I can understand your concern. Primarily it seems to be an infection and do not worry about casts presently. Your PSA (prostate-specific antigen) levels are high which might be due to prostatitis. It needs minimal four weeks of antibiotics (Ciprofloxacin and Metronid...  Read Full »

I am concerned about my PSA and free PSA values. What to do?

Query: Hi doctor,On a recent visit to the doctor, my PSA was 4.7 and free PSA was 0.78. The prostate was swollen on the right side, but no bumps or nodes felt. I had another PSA test three weeks later and the result showed PSA 2.5 and free PSA 0.60. Under what percentage do the 0.78 and the 0.60 values fal...  Read Full »

Dr. Raja Ramesh

Answer: Hello, Welcome to Free PSA (fPSA) and %fPSA (free-to-total prostate specific antigen ratio) are called as PSA derivatives. There is no fixed normal range for fPSA. For your age, in the case of PSA above 4 malignancy or cancer needs to be ruled out by doing a biopsy. The %fPSA helps to d...  Read Full »

Kindly review the MRI of my prostate gland.

Query: Hello doctor, I just recently had magnetic resonance imaging (MRI). I wanted to get your opinion on it. I am a 52-year-old with a genetic father who died of prostate cancer. My prostate specific antigen (PSA) scores have ranged from as high as 3 to as low as 2 in the past couple of years. My most r...  Read Full »

Dr. Andrew Chellakumar Fenn

Answer: Hi, Welcome to I understand your concern. I will get back to you. I am unable to open the files you attached. I have asked for technical support. In the meanwhile, if you could resend the files or re-attach them, as well as contact support, it would be a great help. Sorry for the incon...  Read Full »

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