Common "Prothrombin Gene Mutation" queries answered by top doctors | iCliniq

Prothrombin Gene Mutation

Prothrombin gene mutation or factor II mutation is a genetic condition that increases the risk of developing abnormal blood clots in the lungs (pulmonary embolism) and veins (deep vein thrombosis). There is no treatment, but the doctor may prescribe anticoagulants.

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Will heterozygous Factor-2 Mutation with clotting factors cause miscarriages?

Query: Hi doctor, I am a 43-year-old female with a history of four recent miscarriages in the past 11 months, two chemical pregnancies, one blighted ovum, and one miscarriage at 7.5 weeks after heartbeat not seen at the second ultrasound. I recently discovered I am heterozygous for Factor-2 Mutation, and ...  Read Full »


Dr. Poonguzhali Liston

Answer: Hello, Welcome to icliniq.com. I understand your concern. Clotting factors 1 to 13 are normally present in our body to aid in clotting and bleeding mechanisms in case of injury. The gene that codes for these proteins are inherited from both parents, and any mutation in this will lead to changes in...  Read Full »

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