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How does Tezspire work for asthma?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

The allergist recommended Tezspire for my 16-year-old son's uncontrolled asthma. He has been taking four different medicines already, but still uses a rescue inhaler almost daily and cannot play soccer anymore - it devastated him. The school keeps calling me to pick him up during attacks. This new injection sounds promising, but crazy expensive. Insurance is giving us a headache about covering it. What's this medicine doing differently in his body compared to his other treatments? Is it worth fighting insurance for? How long before we know if it is working? Need straight talk here - his breathing struggles are affecting his mental health, too.

Kindly help.

Answered by Dr. Kaushal Bhavsar

Education:

MBBS

Professional Bio:

Dr. Kaushal Bhavsar is an experienced Internal Medicine Specialist and Pulmonologist with expertise in managing respiratory conditions such as asthma, COPD, tuberculosis, and lung infections, along with chronic illnesses like diabetes, hypertension, and metabolic disorders. He is skilled in critical care, pulmonary function testing, and evidence-based medical management. Dr. Bhavsar is committed to delivering holistic, patient-centered care for long-term health and respiratory wellness.    

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

I have gone through the detailed history you have given. Tezspire Injection (Tezepelumab) (monoclonal antibody) is a newer biologic used for eosinophilic asthma only.

I suggest you do the following tests:

  1. Serum IgE (immunoglobulin E) and eosinophil count.

If these are raised, then only Tezspire will work. It blocks the inflammatory chain reaction caused by chemokines and cytokines.

You need proper justification from a pulmonologist to pass it under insurance.

I hope this helps.

Thank you.

Medically reviewed by iCliniq medical review team
Published At June 14, 2025
Reviewed At June 17, 2025

Education:

MBBS

Professional Bio:

Dr. Kaushal Bhavsar is an experienced Internal Medicine Specialist and Pulmonologist with expertise in managing respiratory conditions such as asthma, COPD, tuberculosis, and lung infections, along with chronic illnesses like diabetes, hypertension, and metabolic disorders. He is skilled in critical care, pulmonary function testing, and evidence-based medical management. Dr. Bhavsar is committed to delivering holistic, patient-centered care for long-term health and respiratory wellness.    

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Kaushal Bhavsar is an experienced Internal Medicine Specialist and Pulmonologist with expertise in managing respiratory conditions such as asthma, COPD, tuberculosis, and lung infections, along with chronic illnesses like diabetes, hypertension, and metabolic disorders. He is skilled in critical care, pulmonary function testing, and evidence-based medical management. Dr. Bhavsar is committed to delivering holistic, patient-centered care for long-term health and respiratory wellness.    

This doctor is not available for online consultations on the platform anymore.

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