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Can Ursodeoxycholic Acid harm the baby during pregnancy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am currently 15 weeks pregnant. At 12 weeks, my SGPT and SGOT levels were elevated, which caused itching. An abdominal ultrasound revealed sludge in my gallbladder. I was prescribed Udiliv 150 mg twice a day, which helped resolve the sludge and brought my liver enzymes back to normal. However, after stopping Udiliv for one week, the itching returned and my liver enzymes increased slightly. My concern is whether Udiliv is safe for my baby, considering I may need to start taking it again even before the anomaly scan and possibly continue it until delivery. I am feeling very stressed and would greatly appreciate your guidance.

Please help.

Thank you.

Answered by Dr. Chibitam Hope Obia

Education:

MBBS

Professional Bio:

Dr. Chibitam Hope Obia is a dedicated General Practitioner and Family Physician with expertise in managing a wide range of acute and chronic conditions. He has a strong interest in mental health and has pursued advanced training in the field. Dr. Obia is known for his patient-centered approach, clinical efficiency, and commitment to holistic care for individuals and families.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

I am very sorry to hear about your medical condition, but I am glad you are paying close attention to the changes in your body. Please do not worry. I am here to support you. Regarding your concerns, it is generally not considered safe to take Udiliv long-term during pregnancy. The relapse you are experiencing is likely due to the pressure exerted by the growing pregnancy on the gallbladder, which can cause elevated liver enzymes and itching when the medication is stopped. However, it is usually recommended to discontinue the medication until after delivery, as most pregnancy-related changes in liver function tend to normalize postpartum.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed by iCliniq medical review team
Published At August 7, 2025
Reviewed At August 7, 2025

Education:

MBBS

Professional Bio:

Dr. Chibitam Hope Obia is a dedicated General Practitioner and Family Physician with expertise in managing a wide range of acute and chronic conditions. He has a strong interest in mental health and has pursued advanced training in the field. Dr. Obia is known for his patient-centered approach, clinical efficiency, and commitment to holistic care for individuals and families.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Chibitam Hope Obia is a dedicated General Practitioner and Family Physician with expertise in managing a wide range of acute and chronic conditions. He has a strong interest in mental health and has pursued advanced training in the field. Dr. Obia is known for his patient-centered approach, clinical efficiency, and commitment to holistic care for individuals and families.

This doctor is not available for online consultations on the platform anymore.

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