Should one be concerned about Brunner's gland hyperplasia?

Question

Hi doctor,

I had an endoscopy done three years back. Recently, I went through the report and it said that I have focal Brunner’s gland hyperplasia (nonspecific) in my duodenal mucosa but the doctor never mentioned this to me. I have GERD and take Prilosec 20 mg tablets daily. Is this serious? The results of my biopsy are as follows:

Received in for main are four tan friable soft tissue fragments ranging from 0.03-0.1 inches in greatest dimensions entirely submitted.

Should this have been removed? Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

We take this opportunity to guide you.

I will review your case history and will get back to you shortly. Kindly revert after getting my detailed response.

Thank you.

Answer 2

Hi,

Welcome to icliniq.com.

Glad to have you back.

My insights are as follows:

0.1 inches is 3 mm which is the normal size of the duodenal mucosal biopsy. (this size was of the biopsy sample, which showed normal duodenal mucosa with some focal area of Brunner's gland hyperplasia). This was not the size of the focal area of the hyperplasia itself.
The treatment of choice for mild esophagitis and gastritis is proton pump inhibitors which you are already taking.
This was an incidental finding and is non-specific. Usually, there is no need to repeat the endoscopy. In your case, the last endoscopy was done three years back. If you want to ensure that your duodenal mucosa looks normal now, you can undertake a duodenal biopsy to recheck if the hyperplasia is fine.
However, from your previous report, there is nothing to worry about.

Wishing you good health.

Thank you.