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Measles and Otosclerosis

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5 min read


The relationship between measles and otosclerosis sheds light on how measles infection can lead to the development of otosclerosis.

Medically reviewed by

Dr. Sugandh Garg

Published At May 17, 2024
Reviewed AtMay 17, 2024


Measles, a highly contagious viral infection, has been a significant public health concern worldwide. While its immediate effects are well-documented, emerging research suggests a potential link between measles infection and the development of otosclerosis, a condition affecting the middle ear.

What Is Otosclerosis?

Otosclerosis is a complex condition that involves abnormal bone remodeling within the delicate structures of the middle ear. This process disrupts the normal mechanisms of sound transmission, resulting in varying degrees of hearing impairment. While the exact cause of otosclerosis remains elusive.

At the heart of otosclerosis lies the stapes bone, one of the smallest bones in the human body and a crucial component of the auditory system. The stapes bone sits within the middle ear, forming part of the ossicular chain. These vibrations are essential for converting sound waves into electrical signals, which the brain interprets as sound.

In individuals with otosclerosis, abnormal bone growth occurs around the stapes bone and adjacent structures. This process, known as ossification, gradually immobilizes the stapes bone, impeding its ability to transmit sound efficiently.

The progression of otosclerosis can vary from person to person. Some individuals may experience mild hearing impairment that progresses slowly over time, while others may develop more severe forms of the condition, resulting in significant hearing loss. Additionally, otosclerosis can affect one or both ears, further complicating the management of the condition.

While the underlying mechanisms of otosclerosis remain the subject of ongoing research, several factors contribute to its development. Genetic predisposition plays a significant role, with a family history of otosclerosis increasing the likelihood of developing the condition. Environmental factors, such as hormonal changes during pregnancy or exposure to certain viruses, may also influence the onset and progression of otosclerosis.

From hearing aids to surgical interventions like stapedectomy or stapedotomy, healthcare professionals have a range of tools at their disposal to address the challenges posed by otosclerosis and restore auditory function.

What Are Measles?

Measles, also known as rubeola, is a highly contagious viral infection caused by the measles virus (MeV), belonging to the Paramyxovirus family. It primarily affects the respiratory system but can lead to systemic complications, particularly in unvaccinated individuals or those with compromised immune systems.

Measles has a distinctive red rash, a high fever, and other flu-like symptoms. While measles was once a common childhood illness worldwide, widespread vaccination efforts have significantly reduced its prevalence in many regions. However, outbreaks still occur, especially in areas with low vaccination rates or where vaccination campaigns are disrupted.

The measles virus can lead to serious complications, especially in vulnerable populations such as young children. Complications may include pneumonia, encephalitis (brain inflammation), and, in severe cases, death.

What Are the Symptoms of Otosclerosis?

The symptoms are mentioned below:

  • Gradual Hearing Loss: Otosclerosis often presents as a slow and progressive hearing loss, typically beginning in one ear and eventually affecting both ears. Initially, individuals may notice difficulty hearing soft sounds or conversational speech, particularly in noisy environments. Hearing loss may become more pronounced as the condition progresses, making it challenging to follow conversations.

  • Tinnitus (Ringing in the Ears): This phantom sound can vary in intensity and may be continuous or intermittent. Tinnitus often accompanies hearing loss and can exacerbate feelings of frustration, anxiety, or distress for individuals living with otosclerosis. While the exact mechanism underlying tinnitus in otosclerosis is not fully understood, it is believed to result from changes in the auditory system due to abnormal bone growth and impaired sound transmission.

  • Dizziness or Vertigo: In some cases, otosclerosis can lead to episodes of dizziness or vertigo, characterized by a spinning sensation or imbalance. This symptom, known as vestibular dysfunction, occurs when abnormal bone growth affects the inner ear structures responsible for balance and spatial orientation. Individuals with otosclerosis may experience dizziness or vertigo during sudden head movements, changes in position, or as a result of pressure changes within the middle ear. While not as common as hearing loss or tinnitus, vestibular symptoms can significantly impact daily activities and balance.

  • Sound Sensitivity (Hyperacusis): Some individuals with otosclerosis may develop a heightened sensitivity to certain sounds, known as hyperacusis. Even normal sounds may become uncomfortably loud or overwhelming for individuals with hyperacusis, leading to avoidance behaviors and social withdrawal. Hyperacusis often coexists with hearing loss and tinnitus in otosclerosis and can further contribute to communication difficulties and emotional distress.

  • Ear Pressure or Fullness: Some individuals with otosclerosis also report sensory signals of ear pressure or fullness. This symptom may arise due to changes in middle ear pressure caused by abnormal bone growth or inflammation. Ear pressure or fullness can be intermittent or persistent and may fluctuate in severity over time. While typically not as debilitating as hearing loss or vertigo, ear pressure or fullness can still cause discomfort and affect an individual's overall well-being.

What Are the Causes of Otosclerosis?

Otosclerosis is a multifactorial condition, with various factors believed to contribute to its development.

  • Genetic Predisposition: Genetic factors are believed to play a significant role in otosclerosis. The condition often runs in families, suggesting an inherited predisposition. Multiple genes have been implicated in otosclerosis, although the exact genetic mechanisms underlying the condition are still being investigated. Variations in genes related to bone metabolism and inflammation may contribute to abnormal bone remodeling in the middle ear, leading to the characteristic features of otosclerosis.

  • Hormonal Factors: Hormonal changes, particularly during pregnancy, have been associated with the exacerbation of otosclerosis symptoms. It is not uncommon for women to experience worsening hearing loss or tinnitus during pregnancy or shortly after giving birth.

  • Measles Infection: Emerging research suggests a potential link between measles infection and the onset of otosclerosis. The measles virus (MeV) triggers an inflammatory response in the body, including the middle ear. This inflammatory process may disrupt normal bone homeostasis and lead to abnormal bone growth. While the exact mechanisms by which measles infection contributes to otosclerosis are not fully understood, evidence from epidemiological studies and animal models supports a possible association between the two conditions.

  • Other Environmental Factors: Environmental factors, such as exposure to certain toxins or viral infections other than measles, may also contribute to the development of otosclerosis. Chronic exposure to loud noise, smoking, and certain medications have been implicated as potential risk factors for otosclerosis or exacerbating its symptoms.

What Is the Treatment for Otosclerosis and Measles?

Treatment of Otosclerosis:

  • Hearing Aids: In the early stages of otosclerosis, when hearing loss is mild to moderate, hearing aids can effectively improve auditory function. Hearing aids amplify sound and help individuals better perceive speech and other sounds.

  • Surgical Intervention: Surgical procedures may be recommended for individuals with more advanced otosclerosis or significant hearing loss. The two primary surgical options for otosclerosis are:

  • Stapedotomy: In this minimally invasive procedure, a small hole is drilled in the stapes footplate, allowing for improved bone movement and better transmission of sound vibrations.

  • Medications: While medications cannot reverse the bone changes associated with otosclerosis, they may help slow down the condition's progression in some cases. Sodium fluoride, a medication that promotes bone remineralization, has been used to inhibit the growth of otosclerotic bone and preserve hearing in certain individuals.

  • Management of Symptoms: Treatment may also involve managing associated symptoms such as tinnitus or dizziness. Techniques such as sound therapy or vestibular rehabilitation exercises can help individuals cope with these symptoms and improve their quality of life.

Treatment of Measles:

  • Supportive Care: There is no specific antiviral treatment for measles, so treatment primarily focuses on managing symptoms and supporting the immune system's response to the infection.

This may include:

  • Rest: Adequate rest is essential for helping the body fight off the infection and recover.

  • Symptom Management: Antihistamines may help relieve itching associated with the rash, while cough suppressants or decongestants can alleviate respiratory symptoms.

  • Vitamin A Supplementation: In regions where vitamin A deficiency is prevalent, supplementation with vitamin A may be recommended to reduce the risk of complications and improve outcomes, especially in young children with measles.

  • Preventive Measures: Vaccination remains the most effective means of preventing measles infection. The measles, mumps, and rubella (MMR) vaccine is highly effective in providing immunity against measles and is typically administered in two doses, starting in childhood.


The relationship between measles and otosclerosis underscores the importance of vaccination in preventing measles infection and potential long-term complications such as otosclerosis. Doctors remain vigilant in monitoring patients with a history of measles infection for signs of otosclerosis and provide timely interventions to mitigate its impact on hearing health.

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Dr. Sugandh Garg
Dr. Sugandh Garg

Internal Medicine


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