AFP is termed alpha-fetoprotein. It is a protein that is formed in the liver of a developing baby. It remains high in newborn babies and will reduce in levels by the age of 1. Healthy adults should have low levels of AFP in their bodies. An AFP tumor marker test is a blood test that measures the level of AFP in healthy adults. It helps to detect cancers of the liver, testicles, and ovaries. Elevated levels of AFP indicates the presence of germ cell tumor or primary lung cancer in the body.

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Does increased AFP level in triple marker test confirm anomalies in the baby?

Query: Hi doctor, What should be the AFP level in the triple marker test? In the triple marker test, we had a high level of AFP 174 at 18 weeks. Should we be worried? The hCG is 73382, and estriol is 0.88. What to do next just got the report, and very tense. Kindly give your opinion.  Read Full »

Dr. Poonguzhali Liston

Answer: Hello, Welcome to The AFP is basically alpha-fetoprotein which is produced by your baby's body only. The triple test is done to look for or predict any anomalies or defects in the baby. It is a screening test. AFP is to predict the presence of neural tube defects (spine and brain). ...  Read Full »

What does high ranges of ALT and AFP in blood reports indicate?

Query: Hi doctor, I have had a standard blood test, and I am worried about the results. Most things seem in the upper range apart from the ALT at 118 and AFP 13. I am 32 years old, fit, with no symptoms, and not a massive drinker. Can I have your suggestion?  Read Full »

Dr. Zubayeralam

Answer: Hi, Welcome to Thanks for the query. I can understand your concern. According to your statement, you have recently done some blood tests, and your reports (attachments removed to protect the patient's identity) have shown that ALT is 118 IU/L (<41) which is above normal, and AFP i...  Read Full »

Will they remove the entire ovary in the case of ovarian cyst?

Query: Hi doctor,A few months ago, I had an ultrasound for some cyst pain. A small growth was discovered on my ovary along with a large cyst as you can see from the documentation attached to this question. I am trying to do everything I can to avoid losing this ovary. My question is, after reviewing the a...  Read Full »

Dr. Ashwini Nanasaheb Talpe

Answer: Hi, It looks like the right ovary is having a complex ovarian cyst. It could be malignant also (attachment removed to protect patient identity). Please get alpha-fetoprotein AFP, HCG (human chorionic gonadotropin) and CEA carcinoembryonic antigen. Depending upon the diagnosis you shoul...  Read Full »

The doctor has a hard time explaining these tumor marker test results. Can you?

Query: Hello doctor, I was just curious what your translation of this might be. I am copying this information directly from a printout of medical records which I can upload if necessary. This is the tumor marker test results of a 70 year old white male. Reports from three years ago: CEA 1.4 ng/mL AFP-tu...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post and investigations. AFP means alfa-fetoprotein. It is elevated commonly in three conditions which are: Liver cell carcinoma. Hepatitis.  Germ cell tumors. You have reported two different levels, one is 18 and the other is more than 26 thousand...  Read Full »

Please explain my AFP and serum tumor marker test results.

Query: Hello doctor,I had some lab work done and this was part of the blood test AFP, serum tumor marker 1.9, 0.0-8.3 (ng/mL). Can you please explain this to me? Five years back, I had a complete laryngectomy and a flap. So, I breathe through a stoma but my doctor did all the tests and found polyps and liv...  Read Full »

Dr. Y Siva Roja

Answer: Hello, Welcome to I have thoroughly reviewed your query. The laboratory investigation under discussion here is alpha-fetoprotein (AFP), which in your case might have been done to rule out a possible malignancy of liver (it is a common tumor marker used to screen hepatic or liver carci...  Read Full »

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