Common "Androgen Insensitivity Syndrome" queries answered by top doctors | iCliniq
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Androgen Insensitivity Syndrome

A genetically male person with one X and one Y chromosome is resistant to male hormones or androgens. As a result, the person has male genetics but some physical characteristics of a woman. This condition is called androgen insensitivity syndrome (AIS).

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My sister's report shows 46 XY chromosome. What is this?

Query: Hi doctor, My sister is 18 years old, and she has never had periods. Recently, we did a test which said, 46, XY (20), 20 cells were counted, all cells showed 46 chromosomes. Small chromosomal anomalies and small clonal population may not be detected using the standard methods employed. Could you ple...  Read Full »

Dr. Balakrishnan R

Dr. Balakrishnan R

Answer: Hi, Welcome to icliniq.com. 46 chromosomes mean the total number of chromosomes is normal. For a normal female, the sex chromosome should be "XX". "XY" means male. So, your sibling who is looking as or phenotypically female is actually or genotypically a male.This is mostly androgen insensitivity s...  Read Full »

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