Azathioprine

Azathioprine is a prodrug that belongs to the immunosuppressant drug group and is used in autoimmune disorders like systemic lupus erythematosus, Crohn's disease, ulcerative colitis, rheumatoid arthritis, pemphigus, Behcet's disease, myasthenia gravis, and in organ transplant patients to prevent graft rejection. Side effects include nausea, vomiting, bone marrow suppression, acute pancreatitis, and increased cancer risk. Therefore, it is contraindicated in pregnant and lactating women.

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Is it fine to take Prednisone and Azathioprine for autoimmune hepatitis?

Query: Hi doctor, I have been itching throughout my body, especially after eating, for about two years. I noticed fatigue and shortness of breath about 18 months ago. I stopped smoking before seven years. I stopped drinking before a year as my upper abdominal area started paining after drinking. Before fi...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. There are a few important facts I would want you to consider. We have to rule out other forms of hepatitis like viral hepatitis, amyloid or iron deposition, NASH (nonalcoholic steatohepatitis) and alcoholic liver disease. All three markers are non-specific; an...  Read Full »

What is the treatment for focal segmental glomerulosclerosis in a 12-year-old?

Query: Hello doctor, My 12 year old son is suffering from nephrotic syndrome since the last seven years. Two years ago, when his biopsy was done, the result said FSGS. His creatinine levels at that time was 4. Now it is raised to 10.1. He is currently taking Calcium, Folic acid, Pantoprazole, Sodium bicar...  Read Full »


Dr. Geetha Priyadarsini Kamminana

Answer: Hello, Welcome to icliniq.com. Please furnish the following medical information, so that I will be able to give you further advice. What is the cause of focal segmental glomerulosclerosis (FSGS)?Has dialysis been done? What is his urine output?What does his antinuclear antibody (ANA) profile say?Ha...  Read Full »

Why do I have multiple itchy lesions all over my body?

Query: Hello doctor, I am 72 years male, who weighs 66 kg and I am 166 cm tall. I have multiple itchy lesions all over my body which responses temporarily to oral steroids. RAST test showed I am allergic to dogs and cats. My dermatologist diagnosed it as type 3 hypersensitivity (IgG mediated), and I am no...  Read Full »


Dr. Suvash Sahu

Answer: Hi, Welcome to icliniq.com. I have read your query. It seems you have developed either allergic contact dermatitis or tinea corporis. Please sent pictures of the lesions, for a better understanding. Revert with more information to a dermatologist online --> https://www.icliniq.com/ask-a-doctor-o...  Read Full »

What does stress have to do with Crohn's disease?

Query: Hello doctor, I have Crohn's disease. Two years back, I was fine. I had gone through extreme stress early that year and after that, I had a flare-up. I lost 9 kg in a month. Then, the doctors detected ulcers in my ileum I was diagnosed with Crohn's. I was out of work for 14 months. Assuming that it...  Read Full »


Dr. Vadivel Kumaran. S

Answer: Hi, Welcome to icliniq.com. You have a very good treatment response to Adalimumab. You are on top-down therapy. Usually, flares are due to non-compliance with medications, secondary infections or malignant transformation. Usually, stress does not cause flare-ups. You may be switched back to Pent...  Read Full »

What kind of dietary changes should I make if I have Crohn's disease?

Query: Hi doctor, I have Crohn’s disease. I would like to know how long it takes for the affected area of the small bowel to end up causing scarring (scar tissue). Do you feel if I have a lower number CRP on regular blood tests, that it should not lead to scarring, thickening or narrowing of the bowel? I...  Read Full »


Dr. Noushif. M

Answer: Hello, Welcome to icliniq.com. Azathioprine helps in controlling the disease and hence should be continued. We cannot say how long it will take for scarring. CRP (C-reactive protein) helps in determining disease activity. It may not correlate with scarring. Not all inflammation results in scarring. ...  Read Full »

Is there any alternate for steroid drugs?

Query: Hello doctor, My son is taking steroids for the past six months, and he is facing a lot of issues concerning the side effects of the medicines. Please have a look at the attached details of the problems faced by him till date. You had also told us that the medication he is taking would have side ef...  Read Full »


Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to icliniq.com. Firstly, most of these side effects are attributed to steroids, which were going on in high doses for the initial few weeks. Now the dose is significantly reduced by his treating doctor to 6 mg only, so most of his side effects will gradually subside. Next, regar...  Read Full »

Kindly suggest the safe drugs for lupus during the third-trimester.

Query: Hello doctor, My wife is 7.5 months pregnant (third trimester). She has been diagnosed with lupus before conceiving. Now she is taking Deflacort 24 mg and taking the Injection Cardinex. She is continuing so. Is it safe to consume Deflacort 24 mg at this phase? She also has an allergy. What shall be...  Read Full »


Dr. Nupoor Acharya

Answer: Hello, Welcome to icliniq.com. You have not mentioned the symptoms of your wife. The treatment of lupus depends on the symptoms and severity of the disease. Some lupus medicines cannot be given during pregnancy. Medicines like Hydroxychloroquine, steroids, Azathioprine are relatively saf...  Read Full »

Please suggest the latest treatment for non-specific interstitial pneumonia.

Query: Hi doctor, For the past five years, I have been suffering from non-specific interstitial pneumonia. Initially, I used Deltacortril and Imuran for a year and then till now I am only using Imuran two tablets in the morning and one in the evening. While going to sleep, I use 1 L/min oxygen. I do like t...  Read Full »


Dr. Amolkumar W. Diwan

Answer: Hello, Welcome to icliniq.com. NSIP, non-specific interstitial pneumonia is a chronic disease of interstitial pneumonia. The treatment of disease runs long term. If you stop the treatment early, there is more chance of relapse and the disease will not be controlled with the same medicines. Coming t...  Read Full »

Will Mometasone help in atropic dermatitis flareup?

Query: Hi doctor, I have been experiencing flare-ups for weeks now. I do not know if this has something to do with the change of weather. I have been having trouble sleeping lately since I am very uncomfortable right now. I am using Cetaphil gentle wash and shampoo because my scalp gets itchy as well. I a...  Read Full »


Dr. Vikash Paudel

Answer: Hi, Welcome to icliniq.com. Atopic dermatitis is relatively more sort of relapsing with seasonal aggravation. It has a genetic and familial component as well. If you have severe symptoms which is hampering your daily activities you need to start with systemic immunosuppressants like Prednisolone ...  Read Full »

What is the treatment for PAN and multiple aneurysms?

Query: Hello doctor, My 21 years old daughter suffered from severe abdominal pain and vomiting one month back. I consulted a local physician for treatment. He gave some antibiotics, but no relief. I consulted gastrologist too. He prescribed some medicines, but no relief. He advised me to do the abdominal ...  Read Full »


Dr. Naval Mendiratta

Answer: Hello, Welcome to icliniq.com. I have gone through your query. The diagnosis of Polyarteritis nodosa looks quite certain. Microaneurysms, high blood pressure, and high CRP are favoring it as well. I understood that she had been started on steroids and Azoran (Azathioprine). My personal recommendat...  Read Full »

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