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What is the prognosis of triple-negative breast cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My mother has been diagnosed with triple-negative breast cancer, and I am trying to understand what to expect moving forward.

  1. How does this type of breast cancer differ from other forms, and what are the specific challenges associated with it?
  2. What treatment options are typically recommended, and how effective are they for someone with this diagnosis?
  3. What should we be prepared for in terms of side effects, potential complications, and overall prognosis?
  4. How can we best support them physically and emotionally throughout their treatment and recovery?

Please help.

Thank you.

Answered by Dr. Mohamed Abdirahman Ali

Education:

MBBS

Professional Bio:

Dr. Mohamed Abdirahman Ali is a skilled and experienced Consultant General and Laparoscopic Surgeon dedicated to providing advanced surgical care. He specializes in minimally invasive laparoscopic procedures, gastrointestinal and abdominal surgeries, and complex general surgical interventions. Renowned for precision, patient-focused care, and evidence-based approaches, Dr. Ali combines technical expertise with compassionate guidance, ensuring optimal outcomes and promoting faster recovery and overall wellness for his patients.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com

I understand your concern, and I am here to discuss your mother's case.

Regarding the condition of triple-negative breast cancer, this type of cancer is progesterone hormone receptor-negative, with HER2 negative as well.

It is an aggressive type, and it needs aggressive chemotherapy followed by surgery (mastectomy with axillary lymph node clearance).

Chemotherapy will be given in different types of regimens for about four months, which your oncologist will tell you about and which you need to consult.

Triple-negative breast cancer prognosis is poor. On the other hand, I would like to know if your mother had any other investigations, such as an MRI (magnetic resonance imaging), a lymph node biopsy status, or any other part of the body involvement (tumor metastasis). This type of tumor survival rate is five years after aggressive treatment.

This type of cancer is aggressive, and hence, strong family support and palliative care play a vital role.

The probable causes are first-degree family history, obesity, use of hormonal replacement therapy, late menopause, and tobacco consumption. Do a mammogram of both breasts, an ultrasound of the axilla, a trucut biopsy of the lump, and a CT (computed tomography) scan of the chest, abdomen, and pelvis. The probable diagnosis is invasive ductal carcinoma.

Aggressive chemotherapy followed by modified radical mastectomy can be given. Do early detection, breast clinical exams, and yearly mammograms. Have a good, healthy diet, exercise, and weight reduction. Do genetic testing for BRCA1 (breast cancer gene 1) and BRCA2 (breast cancer susceptibility gene 2). Avoid radiation and smoking.

Kindly share those investigation reports that you have done. If you have not done it, then consult your oncologist for further investigation.

I hope this answers your query.

Let me know if I need to assist you further.

Thank you.

Medically reviewed by Dr. K. Shobana
Published At October 3, 2024
Reviewed At June 4, 2026

Education:

MBBS

Professional Bio:

Dr. Mohamed Abdirahman Ali is a skilled and experienced Consultant General and Laparoscopic Surgeon dedicated to providing advanced surgical care. He specializes in minimally invasive laparoscopic procedures, gastrointestinal and abdominal surgeries, and complex general surgical interventions. Renowned for precision, patient-focused care, and evidence-based approaches, Dr. Ali combines technical expertise with compassionate guidance, ensuring optimal outcomes and promoting faster recovery and overall wellness for his patients.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Mohamed Abdirahman Ali is a skilled and experienced Consultant General and Laparoscopic Surgeon dedicated to providing advanced surgical care. He specializes in minimally invasive laparoscopic procedures, gastrointestinal and abdominal surgeries, and complex general surgical interventions. Renowned for precision, patient-focused care, and evidence-based approaches, Dr. Ali combines technical expertise with compassionate guidance, ensuring optimal outcomes and promoting faster recovery and overall wellness for his patients.

This doctor is not available for online consultations on the platform anymore.

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