Patient's Query
Hello doctor,
I am a 49-year-old female, living with metastatic breast cancer that has spread to my bones. Currently on hormonal therapy plus injections. Lately, I feel more fatigue and bone pain, especially in my hips.
I have a few concerns, such as:
Is it a sign that cancer is progressing?
I read about new targeted therapies and immunotherapy. Are they suitable for ER+ HER2- cases like mine?
How do doctors decide when to switch treatments?
Kindly suggest.
Hello,
Welcome to icliniq.com.
I understand your concern.
I am truly sorry that you have been diagnosed with metastatic breast cancer, but I want to reassure you that there are many effective treatment options available today.
Since your tumor is HER2 (human epidermal growth factor receptor 2)-negative but ER (estrogen receptor)-positive and PR (progesterone receptor)-positive, you can benefit from several forms of targeted hormonal therapy, such as Palbociclib, Fulvestrant, and Everolimus. These treatments are designed to control the disease and improve the quality of life.
We usually decide to start them when symptoms begin to progress despite chemotherapy. As for the bone pain you have been experiencing, there are several strategies we can use to help manage it.
Denosumab is a monthly injection that helps reduce bone pain, strengthen the bones, and limit further spread to them.
Localized radiotherapy can also be applied to the painful area, and painkillers can be used according to your pain level, starting from non-steroidal anti-inflammatory drugs, then weak opioids, and if necessary, stronger opioids.
I want you to hold on to hope and never lose it. Palliative radiotherapy, targeted, and hormonal therapy can also be beneficial.
Every day, new medications are being developed that help us overcome cancer-related challenges and gain better control over the disease. It is also very important to focus on proper nutrition and hydration, and if you are able to do some mild exercise, it can make a positive difference.
Emotional support from your family is essential, and joining a support group can also help you share your experience with others who understand what you are going through.
I hope all this information has been clear and helpful for you, and please remember that you can reach out anytime if you have any questions or need further guidance. I am always here for you.
Do follow up with me after seven days.
Regards.
Was this conversation helpful?
Answered byDr. Shimaa Abdelatti Osman
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
Related Questions
Advancements in Lung Cancer Immunotherapy: Everything One Need to Know
Therapeutic Advances in Cancer Immunotherapy - A Successful Course of Therapy
What causes bone pain and occasional bouts of imbalance?
I have bone pain. Could my urothelial cancer be spreading?
Breast Cancer and Hormonal Birth Control: Is There a Risk?
Breast Cancer - Causes, Symptoms, Types, Risk Factors, Diagnosis, Treatment, and Precautions
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.