Calcineurin Inhibitors

Calcineurin activates T cells of the immune system, which can result in an autoimmune response. Calcineurin inhibitors are drugs that block the action of calcineurin and prevent the action of the immune system. This group includes drugs like Ciclosporin, Voclosporin, and Tacrolimus. These drugs are used for rheumatic diseases, schizophrenia, and organ transplantation.

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What is the treatment for focal segmental glomerulosclerosis in a 12-year-old?

Query: Hello doctor, My 12 year old son is suffering from nephrotic syndrome since the last seven years. Two years ago, when his biopsy was done, the result said FSGS. His creatinine levels at that time was 4. Now it is raised to 10.1. He is currently taking Calcium, Folic acid, Pantoprazole, Sodium bicar...  Read Full »


Dr. Geetha Priyadarsini Kamminana

Answer: Hello, Welcome to icliniq.com. Please furnish the following medical information, so that I will be able to give you further advice. What is the cause of focal segmental glomerulosclerosis (FSGS)?Has dialysis been done? What is his urine output?What does his antinuclear antibody (ANA) profile say?Ha...  Read Full »

Is lichen sclerosus a contagious disease?

Query: Hi doctor, I have been diagnosed with lichen sclerosus around my vulva a few months ago through biopsy. I am regularly using Dermol 500 lotion instead of soap to wash the area and applying Dermovate cream. However, I have developed a cut in the skin at the back of my vagina, which is not healing now...  Read Full »


Dr. Muhammad Majid Hanif

Answer: Hi, Welcome to icliniq.com. I have thoroughly gone through your case and can well understand your genuine health concerns. Thanks for taking time to upload latest pictures (attachment removed to protect patient identity) of the lesions on both partner's genitalia.  Read Full »

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