Calprotectin

Calprotectin is a protein produced by neutrophils. While having inflammation in the gastrointestinal mucosa, neutrophils enter this place and release calprotectin. So there are raised levels in the stool. The other causes are bacterial infection, mild diverticulitis, and some medications.

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Can double-balloon enteroscopy with biopsy diagnose Crohn's disease?

Query: Hi doctor, I am a 21-year-old female with a weight of 45 kilograms and a height of five feet four inches. I had symptoms of Crohn's disease without any visible lesions. I got dark blood in my bowel movements with constipation, diarrhea, urgency, nausea, abdominal pain, and weight loss. Every six to...  Read Full »


Dr. A V Hussain Shihaz

Answer: Hi, Welcome to icliniq.com. Having recurrent symptoms for a long duration with very high stool calprotectin levels strongly suggests Crohn's disease. Treatment cannot be usually started with some evidence such as biopsy or imaging. You have not mentioned whether random biopsies were taken during c...  Read Full »

I was told I may have Crohn's. What should I do?

Query: Hello doctor, I am a 48 year old female. History of malnutrition caused by stomach issues that still have not been officially diagnosed but I am told I may have Crohn's. I have chronic pain and seeing a pain specialist for stomach and migraine-related pain. My symptoms are: Severe fatigue. Body...  Read Full »


Dr. Mahmoud Ahmed Abelrahman Abouibrahim

Answer: Hello, Welcome to icliniq.com. Calprotectin is a simple non-invasive stool test that can exclude Crohn's disease. Regarding your stomach pain, I suggest that you take Controloc 40 mg (Pantoprazole) once daily at morning. It is very effective. Consult your specialist doctor, discuss with him or he...  Read Full »

Please advise medications for decreased appetite and increased calprotectin in IBS.

Query: Hello doctor, My son is 22 years old. One and a half years back, he had IBS and piles with loss of weight. CT showed enlarged lymph nodes in the intestine. Neddle biopsy of the same was found to be reactive. However, last year, weight is not improved but reduced (62 to 57 kg). Appetite fluctuates w...  Read Full »


Dr. Rahul Ramakrishnan

Answer: Hi, Welcome to icliniq.com. I went through your son's medical history and would like to advise the following. If the diagnosis is already made of IBS and nothing else, then we need to see this as a case of IBS (irritable bowel syndrome). Weight loss in spite of eating well could be of some conce...  Read Full »

How to reduce calprotectin in Crohn's disease naturally?

Query: Hello doctor, How to reduce calprotectin for Crohn's disease naturally? My cousin has been diagnosed with Crohn's disease three months back. Earlier, he had diarrhea, but now he is more controlled with foods, and there are no symptoms. But the calprotectin test resulted as 305 ug/g. His ESR and CRP...  Read Full »


Dr. Ishwar Chandra Rai

Answer: Hello, Welcome to icliniq.com. I can understand your concern. It is very common to high level of calprotectin in stool. Because Calprotectin is a protein released by a neutrophil during inflammation in gastrointestinal tract. Crohn's disease is an inflammatory condition that is why Calprotectin i...  Read Full »

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