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How can one travel to cholera-hit areas without the vaccine?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I leave for my trip to a Western country tomorrow, and I have not taken any of the cholera vaccine doses yet. Should I still take one now, or should I just skip it? Will a single dose still help?

Kindly suggest.

Hello,

Welcome to icliniq.com.

I understand your concern.

Given that your trip to a Western country tomorrow, taking a cholera vaccine dose now may still offer some protection, but its effectiveness depends on several factors. The CDC (Centers for Disease Control and Prevention) recommends that travelers visiting areas with cholera outbreaks or where food and water safety is questionable should consider getting vaccinated. However, the vaccine typically requires at least ten days to become fully effective. There are different types of cholera vaccines, and their effectiveness varies. For example, the Vaxchora vaccine was approved and has been shown to reduce the risk of moderate and severe diarrhea by 90 percent within ten days of vaccination in people aged 18 to 45.

Considering your time constraint, a single dose might provide some short-term protection, but it is important to weigh the benefits against the time frame. A study found that one dose of a killed whole-cell oral cholera vaccine (kOCV) can offer similar short-term protection as two doses, although the protection may decrease over time. Given your situation, it is crucial to consult a healthcare professional or a travel clinic as soon as possible to discuss your options. They can assess your case and provide personalized advice. In addition to vaccination, practicing good hygiene and taking precautions to avoid contaminated food and water during your trip are essential.

I hope this helps you.

Thank you.

Medically reviewed byiCliniq medical review team

Published At February 25, 2025
Reviewed AtFebruary 26, 2025

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