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How to manage psoriasis with schizophrenia drugs?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 27-year-old male and I have had psoriasis covering 85 percent of my body since starting Clozapine. The psychiatrist says it is finally controlling schizophrenia after 15 failed medicines but the skin is falling off. I tried every cream the dermatologist gave, but nothing worked. Sedation from Clozapine is so bad that one can not even apply creams properly. I am hearing voices. Is it real or hallucinations?

Please help.

Thank you.

Answered by Dr. Georges Hany Kozah

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I can understand your concern.

It sounds like you are experiencing severe side effects from Clozapine, including both the psoriasis flare and extreme sedation, which can make managing the skin condition challenging. Psoriasis can indeed worsen on Clozapine, and the voices you are hearing could be related to the schizophrenia itself or a side effect of the medication.

It is important to consult both your psychiatrist and dermatologist immediately to reassess the treatment plan. Alternatives like biological treatments for psoriasis or adjusting the antipsychotic medication may be necessary. The voices are likely hallucinations related to schizophrenia, but it is crucial to work with your psychiatrist to address these symptoms as well.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed by iCliniq medical review team
Published At February 26, 2025
Reviewed At February 26, 2025

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

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