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Does my baby have a higher risk of Down syndrome?
Query: Hi doctor, My wife had NT scan and double marker test at 12 weeks and 3 days of pregnancy. The report is as follows, CRL is 59.2 mm, NT is 1.45 mm, free beta-hCG is 84.84 mIU/mL, equivalent to 2.217 MoM and PAPP-A 0.712 IU/L equivalent to 0.282 MoM. Trisomy 21 is 1: 450 1:47 and trisomy 18 is 1: 531... Read Full »
Answer: Hi, Welcome to icliniq.com. I have read your question and understand the concerns. The report is showing a high risk for trisomy 21or Down's syndrome. This first-trimester screening is 95 % sensitive, hence, if the risk is positive, then the amniocentesis should be done to confirm the fetal karyotyp... Read Full »
Should I be worried about my second-trimester anomaly scan, which is positive for two markers?
Query: Hello doctor, I am a 31 year old female. My first trimester NT and double marker test showed a very low risk of 1:3690 for DS and 1:100000 for two other abnormalities. During the second-trimester anomaly scan, the doctor found two markers, CP cyst and mild RPD 4 mm and 4.5 mm. I have given blood for... Read Full »
Answer: Hello, Welcome to icliniq.com. I have gone through your question and understand the concerns. The risk in serum screening is low. Choroid plexus cyst usually resolves by 26 weeks, if present as a normal variant. A renal pelvis more than 7 mm is abnormal, but more than 4 mm is doubtful. Hence, Ther... Read Full »
What is the risk of Down's in the double marker report?
Query: Hi doctor, This is the report of double marker test of my wife: Corrected MoM and calculated risks: fb-hCG 165 ng/ml 3.82 Corr. MoM PAPP-A 1.84 mlU/ml o.45 Corr. MoM Ultrasound data: Nuchal translucency 1.00 mm CRL 60 mm 0.64 MoM Gestational age by CRL 12+ 2 Nasal bone present Gestational age on th... Read Full »
Answer: Hello, Welcome to icliniq.com. To explain you the report in plain language, first of all, let me tell you that the dual marker test is just a screening test for Down's syndrome and other chromosomal anomalies like trisomy 13/18. So, the test involves calculation of the risk of carrying a Down's... Read Full »
When is double marker test indicated?
Query: Hello doctor, My wife is 28 years old and is in her 13th week of pregnancy. We had an NT test a couple of days back. The NT was 1.7mm. Trisomy 21 had an adjusted scale of 1:3428. Our doctor has advised us to go for a double marker test. The results will be out in two to three days. Is a risk of 1 in... Read Full »
Answer: Hello, Welcome to icliniq.com. The NT (nuchal translucency) test and double marker are dependent on each other. A risk of 1 in 3428 is not considered high. You have been asked to go for a blood test so as to conclude the results, as only NT test is not sufficient. For the double marker, NT measur... Read Full »
What is the risk of baby being born with Down's syndrome?
Query: Hello doctor, My wife underwent double marker test. Results are as follows. Please tell me if there is any risk factor regarding the pregnancy. Her age is 31 years. PAPP-A : 0.35 MoM, fb-hCG 2.14 MoM, age risk 1:743, biochemical T21 risk 1:54, combined trisomy 21 risk 1:226, trisomy 13/18 + NT. Read Full »
Answer: Hello, Welcome to icliniq.com. Yes, there is a risk of the baby being born with Down's syndrome. To confirm it, there is a test called chorionic villus sampling, where the sample of the placenta is taken, and chromosomal analysis is done to rule out trisomy 21, 18, and 13, which are abnormal chrom... Read Full »
What does it indicate if the double marker test in pregnancy is positive?
Query: Hi doctor,I am in my 29th week of pregnancy. NIPT shows low risk but the double marker test is positive. Kindly go through my ultrasound report and please tell me if everything is fine or not. Read Full »
Answer: Hi, Welcome to icliniq.com. I went through your report (attachment removed to protect the patient's identity), these are the interpretations of your USG (ultrasound) report: Single fetus, which corresponds to 29 weeks, is adequate growth according to both ultrasound scans and dates. A weight of... Read Full »
After missing my NT scan and double marker test, can I take it during the 15th to 16th week?
Query: Hello doctor, Now I am in the 14th week of my pregnancy. I missed the NT scan and the double marker test to be taken between the 11th to 14th week of pregnancy. Can I take the NT scan and double marker test between the 15th to 16th week of pregnancy? Read Full »
Answer: Hello, Welcome to icliniq.com. The NT (Nuchal Translucency) scan and the Double Marker test should be done between the 11th to the 14th weeks of pregnancy only because the values are inaccurate if done later. I suggest you calculate the dates based on the first ultrasound as the exact date can var... Read Full »
Can you please interpret the results of my double marker test?
Query: Hi doctor, I want to know about the double marker test results. I am uploading the reports. Read Full »
Answer: Hello, Welcome to icliniq.com. I have seen the reports (attachment removed to protect patient identity) and understand your concern. The result is in the high-risk zone, and the next test would be a quadruple test done after two weeks to check for risk of aneuploidies. Read Full »
My double marker test report is abnormal. Is my baby healthy?
Query: Hi doctor, I had my nuchal translucency scan and double marker blood tests taken a few days ago. I am worried because my NT scan reports are normal, but my double marker test report shows a high risk for trisomy 21. All reports are attached for your guidance and suggestions. Kindly help. Read Full »
Answer: Hi, Welcome to icliniq.com. I hope you are doing well. I read your query, and I can understand your concern. From your history and reports (attachments removed to protect patient's identity), I gather that you are 33 years old, which is a low-risk age, and there are no other risk factors. Previousl... Read Full »
Dual marker test shows high risk for Down's syndrome. Kindly advice.
Query: Hello doctor, I have done a dual marker test. My age is 34 years old. The disorder is Down's syndrome. Result increased. Final risk 1:212. Age risk : 1:433. Cut off : 1:250. Read Full »
Answer: Hello, Welcome to icliniq.com. The risk as mentioned is high. So the next step would be to get a quadruple marker at 14 to 16 weeks and if positive then amniocentesis for fetal cell karyotyping can be done to get a conclusive result to rule out Down's syndrome. If you prefer non invasive test for ... Read Full »