Patient's Query
Hello doctor,
I am 37 years old and was recently told after a biopsy that I have early-stage endometrial cancer. My surgeon is recommending a full hysterectomy, but I have not completed my family yet, and this is very difficult to process. Please tell me,
Is there any fertility-sparing treatment available for my stage?
How effective is it compared to surgery?
What risks am I taking if I choose to delay the operation?
Kindly help.
Hello,
Welcome to icliniq.com.
I read your query and can understand your concern.
At your age, 37, I would like to advise on egg retrieval and preservation. Yes, fertility-sparing treatment can sometimes be considered, but only in very carefully selected cases of early endometrial cancer.
may be possible
Doctors usually allow fertility-preserving treatment only in the following cases:
Grade 1 tumor.
Cancer limited to the endometrium (no myometrial invasion on MRI).
No spread outside the uterus.
The patient accepts strict follow-up with repeated biopsies.
The doctors can use a high-dose progesterone therapy, such as:
Medroxyprogesterone.
Megestrol Acetate.
Sometimes Levonorgestrel Intrauterine System.
These treatments lead to a complete response in about 60 to 80 percent of selected patients.
However, there are some important limitations that you must be aware of.
Cancer can persist or recur in 30 to 40 percent of cases.
An endometrial biopsy is needed every three to six months.
Hysterectomy is usually recommended after completing childbearing.
In your case, the risk of delaying surgery can be significant. If the cancer does not respond or progresses, delaying surgery could allow the disease to advance, which may reduce the chances of a cure. That is why close monitoring is essential.
Surgery remains the most definitive and curative treatment, but fertility-sparing hormone therapy may be an option in very early, low-grade disease with careful follow-up. Discuss in detail with a gynecologic oncologist before deciding.
I hope this information helps you.
Feel free to ask further queries.
Thank you.
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Answered byDr. Neha Nigam
Medically reviewed byiCliniq medical review team
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