Giant Platelet

Giant platelet has a diameter greater than 7 microns, while a normal platelet is between 2 to 3 microns in diameter. Giant platelet disorder is when an individual suffers from thrombocytopenia, bleeds easily, and has giant platelets.

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Are there abnormalities in my blood reports?

Query: Hello doctor,I got a blood test done this week. The investigations are as follows: Red cell distribution width is 11.4 %, platelets count is 130 thou/UI, mean platelet volume is 13.3 fL. Morphology remarks: Gaint platelets are seen, and small clumps of platelets are seen.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Let me tell you that there are abnormalities like high MPV (mean platelet volume) and the presence of giant platelets. This type of picture occurs when there is platelet destruction. So, the bone marrow is stimulated more and hence a lot of premature platelets get ...  Read Full »

What causes high MPV?

Query: Hello doctor, My father is 65 years old. Recently, we went for his routine cardio checkup. His doctor suggested thallium stress test, which was normal. He has been hypertensive for 15 years and is on anti-hypertensive Ramipril 5 mg, Amlodipine 2.5 mg and one diuretic. His BP was high, so the doctor...  Read Full »


Dr. Naresh Kumar Monigari

Answer: Hello, Welcome to icliniq.com. I had gone through all the reports posted (attachment removed to protect patient identity). Mean platelet volume suggests the mean volume of single platelet, which is high and is mostly an incidental finding. Some bleeding disorders like functional defects of platelets...  Read Full »

Can hypothyroidism cause a decrease in platelet counts?

Query: Hi doctor, I had my TSH 7.59 mIU/L before one month. Now my TSH is 5.9 mIU/L. But my platelet count was reduced to 127,000 per microliter of blood. About two weeks ago, I got RPOC after abortion. Now again I have done a CBC. This time also, I had my platelet count 127,000 per microliter of blood and...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. I have reviewed your query and hypothyroidism is not related to low platelet count. Giant platelets are present when there is destruction in platelets. Temporary viral infection, dengue, malaria, uremia, splenomegaly, bacterial infection are some of the causes t...  Read Full »

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