Glimepiride

Glimepiride is a long-acting sulfonylurea antidiabetic drug. It lowers the blood sugar level by increasing insulin release from your pancreas. It is commonly sold under the brand name Amaryl.

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My mother is type 2 diabetic and her level is not dropping even after using medications. What to do?

Query: Hello doctor, My mother has diabetics type 2. Currently, she is using Metformin 500 mg two times a day with Glibenclamide. The problem is it is not dropping as before. Can you please help with other medications or tablets?  Read Full »


Dr. Qazi Mujahid Ali

Diabetologist

Answer: Hello, Welcome to icliniq.com. Your mother needs some different medications, Glimepiride 3 mg before breakfast, Sitagliptin Metformin combination of 50/850 twice daily after meals. Decrease fats in her diet, avoid fast food. Increase physical activity if possible. Sugary things should be avoided a...  Read Full »

My blood sugar is 200 mg/dL. How to reduce it using medicine?

Query: Hi doctor, I am 46 years old. I am diabetic, and I have a high blood sugar level of 200 mg/dL. I also have a hernia problem. Currently, I am taking allopathic medicines, Glimepiride and Metformin. Please suggest.  Read Full »


Dr. Suneetha B S

Diabetologist, Family Physician, Microbiologist, Nutritionist

Answer: Hi, Welcome to icliniq.com. If your blood sugar level is above 200 mg/dL, you may need a change in the dosage of your medication. You might need to increase the dosage of the existing medication, or you may require a new medication. You have not mentioned the exact dosage of Metformin and Glimepir...  Read Full »

What are the possible measures to control diabetes?

Query: Hi doctor, I am taking the following medicines for my diabetes, Amaryl 2 mg 1-0-1, Onglyza 5 mg 0-1-0, Losar A 1-0-0 and Hosit-L 0-0-1 I would like to know if these medicines can control and regulate my diabetes? If not, please advise me some tablet to bring my sugar level down and get better con...  Read Full »


Dr. Hariharan V

Diabetologist, Family Physician, General Medicine Physician, Internal Medicine Physician, Nutritionist

Answer: Hi, Welcome to icliniq.com. I saw your blood reports (attachment removed to protect patient identity) and medications as well. We diabetologists usually give Amaryl (Glimepiride) to young people and Amaryl Plus (combination of Glimepiride and Metformin) for people with long-standing diabetes. I do n...  Read Full »

My sugar levels are high. What to do next?

Query: Hello doctor, I am a 41 year old female. I had GDM 9 years back with twin pregnancy. Post-delivery for few months my blood sugars were normal. Later l was started on tablet Metformin 500 mg SR bd along with diet control. Last year l was started on tablet Atenolol 5 mg od. l feel fatigue even after...  Read Full »


Dr. Divakara P

Diabetologist, Endocrinologist, General Medicine Physician, Internal Medicine Physician, Pain Medicine Physician, Pulmonologist

Answer: Hi, Welcome to icliniq.com. Your blood sugars are quite high and the dose of medication (Metformin 500 mg twice a day) is becoming inadequate for you.  You need to be started on stronger medicine. I would recommend you to take tablet Glycomet GP1 (Glimepiride and Metformin combination) in the morni...  Read Full »

I have diabetes in spite of taking Amaryl and Janumet. Please suggest.

Query: Hello doctor, I am a 51 year old male. I have diabetes. My fasting is 150 to 160 and PP is 250 to 300. I am taking Amaryl 2 mg morning and Janumet 50/1000 after lunch and dinner. Please suggest.  Read Full »


Dr. Nazma Parveen

Family Physician, General Practitioner

Answer: Hello, Welcome to icliniq.com. You are already taking Amaryl (Glimepiride) 2 mg and Janumet 50/1000 (Sitagliptin and Metformin) twice but still, your blood sugar is not under control. Are you following dietary restrictions properly? Your weight is on the higher side. I suggest the dose of Metfor...  Read Full »

How to regulate high blood sugar?

Query: Hi doctor. I am suffering from type 2 diabetes. My last blood sugar level was 400 mg/dL. I am on Insulin. But it is not coming back to normal. What shall I do?  Read Full »


Dr. Hariharan V

Diabetologist, Family Physician, General Medicine Physician, Internal Medicine Physician, Nutritionist

Answer: Hi, Welcome to icliniq.com. Since you have not mentioned the duration of diabetes, I have to assume that you may be having it for a minimum of 5 years. I have seen many patients who start with one drug and maintain sugar at nice levels in that single drug itself. But for many patients, it ...  Read Full »

Can I substitute Amaryl tablet with Kombiglyze tablet?

Query: Hello doctor, I am currently on Amaryl 2 mg. As I will be traveling shortly, to a country where I am told Amaryl is not available, but Kombiglyze is available there. Is it okay to take this substitute?  Read Full »


Dr. Sreejith Mg

General Medicine Physician, Internal Medicine Physician, Diabetologist

Answer: Hi, Welcome to icliniq.com. Amaryl has Metformin 500 mg and Glimepiride 2 mg and Kombiglyze contains Metformin and Saxagliptin. Both combinations are different, so the level of sugar control will be different. Glimepiride is a sulfonylurea and Saxagliptin is a DPP4 (Dipeptidyl peptidase 4) inhibitor...  Read Full »

My HbA1c levels have reduced. Does it mean my diabetes is gone?

Query: Hello doctor, I am a 57 year male. Four months ago, the doctor declared that I am diabetic as my HbA1c was 10.7 %. I started with Glimisave M2 (two tablets per day) and Atorec 10 (one tablet at night), later on, I shifted to Glimisave M1 (two tablets per day) and Atorec 10 as usual. I take other su...  Read Full »


Dr. Shaikh Sadaf

Diabetologist, Endocrinologist, Family Physician, General Practitioner

Answer: Hello, Welcome to icliniq.com. I just read your query. From what you have mentioned, it appears that you have controlled your diabetes quite well. I would suggest that you take tablet Glimisave (Glimepiride) M2 once in the morning and tablet Glimisave M1 once at night. Your diabetes is not gone, but...  Read Full »

My FBS is 220 and RBS is 320. Can I increase my dose of Glimepiride?

Query: Hello doctor, I have diabetes from the last two years. I take medicine Glimepiride 2 mg before breakfast and Metformin 500 mg after meal twice daily. But my routine blood sugar is fasting 220 and random 320 or above. Can I increase my dose of Glimepiride?  Read Full »


Dr. Suneetha B S

Diabetologist, Family Physician, Microbiologist, Nutritionist

Answer: Hello, Welcome to icliniq.com. I understand your concern. Looking at your blood sugar levels, it looks like you definitely need to increase the dosage of your medication. There are three options: Increase dosage of Metformin. Increase dosage of Glimepiride. Add a new drug to the current reg...  Read Full »

Doctor advised taking Insulin injections instead of tablet. What do you suggest?

Query: Hello doctor, I am 33 years old. One year back, my HbA1c result was 8.2. Then, I started to take medicine Dailyglim M1 for three months and started some workout and took light food. Then, my sugar level came down. Fasting and PP result were in 105 and 160 range respectively. But, after some time it...  Read Full »


Dr. Krutika Ingle Karandikar

Diabetologist, Family Physician, General Practitioner

Answer: Hi, Welcome to icliniq.com. I can understand you are hesitant to use Insulin. But what she has said is right. Finally, Insulin is what controls your blood sugars. Since people are hesitant to use it, we usually do not prescribe it as a first-line treatment. Oral medications help the pancreas to p...  Read Full »

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