Hemoglobin A

Hemoglobin A, where A stands for adults, is the widely prevalent hemoglobin tetramer that contains two alpha and two beta subunits. The subunits have a heme group for the binding oxygen molecules, which aids in oxygen transportation from the tissues to the lungs. Deficiency of hemoglobin A results in alpha-thalassemia, beta-thalassemia, and sickle cell anemia.

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Kindly go through my blood report and suggest the type of thalassemia.

Query: Hi doctor,I have attached a report. I just want to know if this hemoglobin electrophoresis result is beta thalassemia minor or beta thalassemia intermedia or beta thalassemia major.  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. According to HPLC report (high-performance liquid chromatography), you have attached, HbA2 raised and HbA decreased (hemoglobin A2 and A). Hence, it is suggestive towards thalassemia minor (attachment removed to protect patient identity). It does not look like thalassemi...  Read Full »

Is my friend's beta thalassemia screening test normal?

Query: Hello doctor, My cousin of 30 years old got tested for beta thalassemia screening test. He got the result as hemoglobin A2 is 2.8 %, hemoglobin F is 0.2 %, hemoglobin C, D and S are not detected. Is this normal or has any complication? Please guide.  Read Full »


Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The beta thalassemia screening test appears to be normal. HbA2 levels (hemoglobin A2) are normally between 2-3.3% and HbF levels (fetal hemoglobin) are 0.1-1.2% for this age. Both are normal. The other hemoglobin type is HbA ...  Read Full »

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