Hemoglobin variant analysis determines the type of hemoglobin and measures the corresponding amount of hemoglobin in the red blood cells. Complete blood count, blood smear examination, hemoglobinopathy evaluation, and genetic testing help identify the variant. Genetic testing studies the alpha and beta globin-producing genes and the deletions and variations seen in them.
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Will HbE trait cause any threat to my baby?
Query: Hi doctor, My son is 1 year and 7 months old. He has hemoglobin E trait. We just got his hemoglobin electrophoresis done and it showed 73% hemoglobin A along with 27% A2 and E. Does this pose a threat? Otherwise, he is a healthy and active kid. He has a slight iron deficiency and for this, we are gi... Read Full »
Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: There is nothing to worry about. As there is no associated thalassemia or other hemoglobinopathy, this is not to be worried about. In the future, during the marriage, he needs to look into hemoglobin electrophoresis of th... Read Full »
What does my hemoglobin variant analysis report indicate?
Query: Hello doctor, I am a 38 year old male. My height is 5'3", and I weigh 69 kg. Recently, I had a health checkup. Please check the attached reports and advise me if any treatment is required. The hemoglobin variant analysis test is showing hemoglobin A 68.6 and hemoglobin S 29.6. Please let me know wh... Read Full »
Answer: Hi, Welcome to icliniq.com. Based on your query and attached reports, my opinion is as follows: (attachment removed to protect patient identity) Increased HbS with reduced HbA at this age suggests possible sickle cell trait disease. Most important evaluation is the possibility of the transfer of ... Read Full »