Common "High Tpo" queries answered by top doctors | iCliniq

High Tpo

TPO, or thyroid peroxidase, is an enzyme necessary for the production of thyroid hormone. High TPO levels indicate an autoimmune reaction against the thyroid gland, also known as autoimmune thyroiditis or Hashimoto's disease. Symptoms of high TPO levels may include fatigue, weight gain, hair loss, cold intolerance, and depression. High TPO levels can lead to hypothyroidism, a condition in which the thyroid gland doesn't produce enough thyroid hormones. A blood test can be used to determine TPO levels, and this is frequently done as part of a standard thyroid panel.

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What do high TSH and TPO antibody levels indicate?

Query: Hello doctor, My TSH is 27 and the anti-TPO antibody test shows more than 600, whereas the normal range is 1-60. Is this a serious condition and what do these numbers indicate?  Read Full »


Dr. Thiyagarajan. T

Answer: Hello, Welcome to icliniq.com. Thank you for your query. Higher TPO antibodies mean that your body's immune system is making antibodies against your thyroid and so as a result your thyroid is not functioning adequately. The pituitary gland senses the low thyroid hormones and makes more TSH (thyroid...  Read Full »

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