How to manage hypothalamic obesity?

Question

Hello doctor,

My child has hypothalamic obesity due to a brain injury, and it is affecting both their physical and mental health. They are becoming more isolated and anxious because of the weight gain. What are the best ways to manage both the physical and psychological aspects of hypothalamic obesity? Are there any medications or therapies that can help reduce weight gain?

Kindly suggest.

Answer 1

Hello,

Welcome to icliniq.com.

I can understand your concern.

Hypothalamic obesity, caused by damage to the hypothalamus from trauma, surgery, or a tumor, disrupts the body's energy balance, leading to rapid weight gain. Liraglutide (brand name Saxenda), a GLP-1 receptor agonist, helps reduce appetite and promote weight loss by slowing down gastric emptying and increasing feelings of fullness. This medication can be continued if well tolerated, but other options may be considered after consulting with your child's doctor.

Other medications like Setmelanotide (Imcivree) target energy expenditure and appetite regulation, while Octreotide can help reduce insulin release and prevent excessive weight gain. Metformin is also used to manage weight. It is important to incorporate regular physical activity, structured meal times, and focus on portion control. Avoiding sugary drinks and processed foods is crucial. Cognitive behavioral therapy (CBT) can help with anxiety and self-esteem. Bariatric surgery may be considered for older patients, but it is not recommended for children due to the risks.

I hope this helps.

Let me know if you have any other concerns.

Thank you.