Knuckle Hyperpigmentation

Knuckle hyperpigmentation occurs due to genetic causes. It often occurs in dark pigmentated people. Dark knuckles can also occur as a symptom of several health conditions. People affected with acanthosis nigrans, dermatosis, vitamin B12 deficiency, and Addison's disease are more prone to develop this skin condition. Knuckle hyperpigmentation is treated depending on the cause. It is usually treated by medication, doing lifestyle changes, and other therapies.

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All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Why do I have red bumps on my knuckles?

Query: Hi doctor,For as many years as I can remember I have these red bumps on my knuckles on the top of my hand. The funny thing is, every time when I am pregnant they disappear. Can you tell me what it could possibly be? I have eczema, but that does not go away during pregnancy.  Read Full »


Dr. Suvash Sahu

Answer: Hi, Welcome to icliniq.com. I have seen your pictures and descriptions (attachment removed to protect patient identity). It looks like knuckle hyperpigmentation. It can occur in certain dermatological conditions like vitamin B12 deficiency, allergic contact dermatitis and SLE (systemic lup...  Read Full »

The skin on the back of my hands is changing color. What is this?

Query: Hello doctor, The skin on the back of my hands is changing color. My skin is dark in some places and lighter in others. My knuckles look darker like they have a black patch. What is this? Currently I am on Alyacen 1/35. I was taking Ferrous sulfate two pills per day.  Read Full »


Dr. G.s.s. Sandeep

Answer: Hello, Welcome to icliniq.com. If possible forward a few pictures of the affected area to guide you through precisely.  Read Full »

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