What is Opdivo immunotherapy for stage 4 NSCLC at 60?

Question

Hello doctor,

I am a 60-year-old male, recently diagnosed with stage 4 NSCLC, and the doctor suggested an immunotherapy drug called Opdivo (Nivolumab). I want to understand before starting treatment. What is Opdivo immunotherapy for stage 4 NSCLC at 60? How does it work, and is it better than chemotherapy?

Please guide.

Answer 1

Hi,

Welcome to icliniq.com.

I am deeply concerned about your worries.

I will explain in simple terms so you can understand clearly. Opdivo (Nivolumab) is a type of immunotherapy used for treating stage 4 lung cancer. Unlike chemotherapy, which directly kills cancer cells, Opdivo helps your immune system recognize and attack cancer cells.

Cancer cells often hide from the immune system by using a pathway . Opdivo blocks this pathway, allowing your immune cells (T-cells) to see and destroy the cancer cells once again.

In many patients, particularly those with certain markers, immunotherapy can be more effective and provide longer-lasting results than chemotherapy.

Some patients achieve long-term disease control. However, it does not work for everyone; while some patients respond very well, others may not see much improvement. Chemotherapy still has a role in treatment, and sometimes both therapies are used together.

Immunotherapy, including Opdivo, is generally better tolerated than chemotherapy. However, it can cause immune-related side effects, such as inflammation in the lungs, skin, thyroid, or intestines. While these side effects are less common, they do require monitoring.

Hope I have addressed all of your queries and concerns.

Thank you.