Lupus Anticoagulant Lca

Lupus anticoagulants (LA) are autoantibodies produced by the immune system that bind to the phospholipids and the proteins associated with the outer-most layer of cells (cell membranes). Lupus anticoagulants interfere with the blood clotting process which may increase an individual's risk of developing a blood clot. Lupus anticoagulant testing is a series of tests used to investigate the presence of lupus anticoagulants in the blood.

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What do positive lupus anticoagulants indicate in the first test of antiphospholipid syndrome?

Query: Hi doctor,I have recently been told my first test of antiphospholipid syndrome shows positive lupus anticoagulants. What does that mean for someone with no symptoms? I took Articaine and Phenphedrine the day before the test. Can an overdose cause the test to be faulty? I had four miscarriages so far...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You have a history of four recurrent miscarriage and cause for that seems to be an antiphospholipid syndrome. Because of thrombosis secondary to antiphospholipid syndrome, miscarriage occurred. If you are on anticoagulant medication, then it could be a false result. But ...  Read Full »

What tests should I do for APS syndrome?

Query: Hello doctor, Following my previous query regarding APS syndrome with immunological features of lupus, I am attaching my latest blood test results. After starting the Plaquenil, my polyarthralgia is less painful than 12 to 18 months ago. Although somewhat slow, the decrease in pain is evident. A...  Read Full »

Dr. Nupoor Acharya

Answer: Hello, Welcome to Good to know that your symptoms are improving. All your test results look normal (attachments removed to protect the patient’s identity). It would be best if you continued getting these tests at regular intervals, as it will help in the early identification...  Read Full »

Does raised dRVVT suggest that I am LA positive?

Query: Hello doctor, I was recently diagnosed with a blood clot in my left jugular vein and put on Eliquis (10 mg twice daily for a week, now 5 mg twice daily). I was also recently diagnosed with some sort of autoimmune disorder, but it is not clear yet which one. After being diagnosed with the blood clot...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to If you have antiphospholipid antibody syndrome(APS) then your anti-cardiolipin antibody or lupus anticoagulant should be positive. Additionally in APS, the raised RVT (renal vein thrombosis) is not corrected by adding normal plasma. So lupus or APS chance seems to be le...  Read Full »

Will vitamin D deficiency during pregnancy affect baby growth?

Query: Hi doctor, My wife is 29 years old and we have a 5 year old son. It was a premature delivery in the 34th week and it was a normal delivery. After that, she had three abortions and all are because of no fetal growth and heartbeat. Currently, she is 10 weeks pregnant. Her recent ultrasound scan sho...  Read Full »

Dr. Sonal Prasad

Answer: Hello, Welcome to The vitamin D levels are in deficient range and vitamin B12 levels are normal. There is no need to discontinue the pregnancy due to these values. Vitamin D supplementation will help to have adequate levels in baby. I suggest vitamin D supplementation Calcirol sachet 60...  Read Full »

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