What is the best immunosuppressant for lupus nephritis?

Question

Hello doctor,

I was diagnosed with lupus nephritis last year, and I feel like my symptoms are getting worse. My legs and face are more swollen. I am feeling exhausted all the time, and my urine has been very foamy. My last lab results showed that my kidney function is not looking great, there is more protein in my urine, and my creatinine levels are creeping up. I am on Prednisone and Mycophenolate, but should we be making any changes? What else can I do to help prevent my kidneys from getting worse?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Lupus nephritis, kidney inflammation caused by systemic lupus erythematosus (autoimmune diseases), is often managed with immunosuppressants, chemotherapy, and corticosteroids, also known as steroids, that suppress your immune system, antimalarial drugs, and blood pressure medicines to prevent damage to your kidneys.

Medicines to treat lupus nephritis might include:

Steroids, such as Prednisone.
Cyclosporine.
Voclosporin.
Tacrolimus.
Cyclophosphamide.
Azathioprine.
Mycophenolate.
Rituximab.

The following play a crucial role in preventing complications:

Exercising regularly.
Following a low-sodium and low-cholesterol diet.
Staying hydrated.
Avoiding alcohol and smoking.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.