Common "Mao Inhibitor" queries answered by top doctors | iCliniq

Mao Inhibitor

Monoamine oxidase inhibitors (MAO) inhibitors are a group of antidepressants that treat depression. They help ease depression by changing levels of brain chemicals (serotonin, dopamine, and norepinephrine) called neurotransmitters. They inhibit an enzyme called monoamine oxidase, which breaks down norepinephrine, serotonin, and dopamine, allowing neurotransmitters to remain in the brain, thus improving mood through improved brain cell communication. Common side effects of MAO inhibitors include headache, dry mouth, dizziness, blurred vision, high blood pressure, muscle cramps, low sex drive, weight gain, blurred vision, nausea, diarrhea, and skin irritations. While taking MAO inhibitors, diet restrictions and avoiding other antidepressants are necessary as they can cause high blood pressure and other medical problems.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Is it fine to take Cardarine while on Nardil?

Query: Hello doctor, I am currently on 90 mg of Nardil (Phenelzine), which has proven to be a miracle drug for me. I have found over the years that many drugs you are supposed to avoid while on MAOIs are really acceptable. For instance, in order to counteract the daytime sleepiness side effect, I am actu...  Read Full »


Dr. Qureshi, Danish Shaikh

Answer: Hello, Welcome to icliniq.com. I understand your concern. Yes, you are right. Bupropion is contraindicated with MAO inhibitors (monoamine oxidase inhibitors) as it may cause seizures. Daytime sleepiness is very hard to avoid, but you may try some natural stimulants like green tea and if needed you c...  Read Full »

I have severe depression. Can dopamine agonists help?

Query: Hello doctor, I have ongoing horrible depression, I have tried TMS, every SSRI, Ketamin, and electroshock. I take Ritilin, Colonpin, Levothyroxine, and Ambien. Would a dopamine agonist possibly help with depression when all others have failed? Please suggest.  Read Full »


Dr. Aditya Gupta

Answer: Hello, Welcome to icliniq.com. It is a refractory depression. There are a few pieces of evidence to show that dopamine agonists like Pramipexole may help in such cases. 1. Adding Bupropion (Ethyl cellulose aqueous dispersion (NF), glyceryl behenate, methacrylic acid copolymer) to SSRI (selective ...  Read Full »

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