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What is the best treatment for melasma in a 25-year-old?

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Patient's Query

Hello doctor,

I am a 25-year-old female seeking treatment for melasma. What is the best medicine for it? Please help.

Thank you in advance.

Answered by Dr. Sofia John

Education:

MBBS

Professional Bio:

Dr. Sofia John is a skilled general practitioner, surgeon, and hair transplant surgeon with a focus on general surgery. She provides patient-centered care through precise evaluation, clear communication, and safety-focused decision-making, supporting patients confidently across medical and surgical needs.  

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I read your query and can understand your concern.

Topical treatments for melasma (a common skin condition causing brown or grayish patches, usually on the face):

  1. Hydroquinone: A skin-lightening agent that reduces melanin production. It is available over-the-counter (2 percent) and by prescription (4 percent) and should be used under dermatological supervision.

  2. Azelaic acid: A milder alternative that inhibits pigment production and is safe for sensitive skin.

  3. Cysteamine cream: A newer treatment that reduces melanin and fades dark spots. It is considered safer than Hydroquinone for long-term use.

  4. Tranexamic acid: Used orally for more severe cases to reduce pigmentation from within. This should be prescribed by a healthcare professional.

Sun protection:

Daily use of a broad-spectrum sunscreen with SPF (sun protection factor) 30 or higher is essential. Sun exposure worsens melasma, even on cloudy days. Sunscreens that block visible light, such as those containing iron oxide, are especially beneficial.

Professional treatments:

  1. Chemical peels: Mild peels using Glycolic acid, Salicylic acid, or Trichloroacetic acid (TCA) help remove pigmented skin cells and encourage skin renewal. These must be done by a dermatologist to minimize irritation.

  2. Laser treatments: Lasers like Q-switched (lasers emit short, high-intensity pulses of light that break down pigment particles in the skin into smaller fragments) and fractional lasers (they create tiny, controlled micro-injuries in the skin by delivering laser beams in a grid-like pattern) target pigmentation without harming the surrounding skin. However, they must be used carefully, as improper use can worsen pigmentation.

Important tips:

  1. Avoid self-medication; always consult a dermatologist before starting treatment, especially with prescription products.

  2. Monitor your skin’s response and stop treatment if irritation occurs; seek medical advice if needed.

  3. Consistency is crucial; visible results often take six to 12 weeks of regular treatment.

I hope this helps.

Kindly revert so I can assist you further.

Thank you.

Answered by Dr. Sofia John
Medically reviewed by iCliniq medical review team
Published At August 21, 2025
Reviewed At August 21, 2025

Education:

MBBS

Professional Bio:

Dr. Sofia John is a skilled general practitioner, surgeon, and hair transplant surgeon with a focus on general surgery. She provides patient-centered care through precise evaluation, clear communication, and safety-focused decision-making, supporting patients confidently across medical and surgical needs.  

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Sofia John is a skilled general practitioner, surgeon, and hair transplant surgeon with a focus on general surgery. She provides patient-centered care through precise evaluation, clear communication, and safety-focused decision-making, supporting patients confidently across medical and surgical needs.  

This doctor is not available for online consultations on the platform anymore.

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