Common "Metaplasia" queries answered by top doctors | iCliniq
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Metaplasia

Metaplasia is when one type of specialized cell changes into another kind of specialized cell. It can occur anywhere in the body. Metaplasia occurs due to an alternate differentiation pathway of stem cells. External stressors induce different gene expressions promoting differentiation to a different cellular pathway. The common types of metaplasia include intestinal metaplasia, squamous metaplasia, oncocytic metaplasia, and tubal metaplasia. An example of metaplasia is smoking causes the replacement of normal columnar bronchial epithelium by squamous epithelium.

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Query: Hi doctor, After testing positive for celiac disease, I had an EGD and biopsy three weeks ago. The pathology report stated that I had marked acute and chronic inflammation with severe reactive epithelial changes including villus blunting and gastric metaplasia. I was negative for H. pylori as I was ...  Read Full »

Dr. Goswami Parth Rajendragiri

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Here according to your history, you were positive for gluten disease. So, you might have done tissue transglutaminase antibody testing. It is very sensitive for that and then, a biopsy for confirmation. In histopathology report, villous blunting present but intra-epithe...  Read Full »

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