Common "Monospot Test" queries answered by top doctors | iCliniq

Monospot Test

The monospot test, also known as the mononuclear test, is a type of antibody test used for infectious mononucleosis due to the Epstein-Barr virus (EBV). This test is performed by placing a sample of blood on a slide, a test strip, or other testing devices.

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How accurate is monospot test for infectious mononucleosis?

Query: Hello doctor, My test is positive for infectious mononucleosis. But my EBV IgM is negative. How accurate Monospot test is? One week abdominal pain and severe throat pain were there.  Read Full »


Dr. Pawar Satyajit Jalinder

Answer: Hello, Welcome to icliniq.com. Monospot test has high sensitivity but it is not so accurate. It can come positive in other infections like rubella, CMV (cytomegalovirus), HIV, toxoplasmosis, and other diseases like SLE. So, if EBV IgM is negative then chances of it being infectious mononucleosis i...  Read Full »

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